medigraphic.com
Anales de Otorrinolaringología Mexicana

2020, Number 4

<< Back Next >>

Otorrinolaringología 2020; 65 (4)

Melanoma of the nasal mucosa

Romo-Magdaleno JA, Busto-Ruano JP, Reyes-Ortega LM

Language: Spanish
References: 27
Page: 191-198
PDF size: 275.91 Kb.


ABSTRACT

Background: Mucosal melanoma of the head and neck is an infrequent disease, with a high mortality rate. Its poor prognosis can be explained by the complexity of the anatomy on these areas, its silent growth and their high capability for metastasis. The lack of knowledge, treatment protocols and series of clinical cases make the approach of patients controversial and subject to diverse therapeutic approaches. Therefore, despite previous research, it has not been possible to increase the survival rate for these patients.
Clinical case: An 89-year-old male patient with a one-year evolution nasal tumor causing nasal obstruction, purulent rhinorrhea, hyposmia, epistaxis and epiphora. A histopathological report of primary melanoma of the nasal mucosa was documented. Due to its statistics and in conjunction with the department of radio-oncology and medical oncology, surgical treatment was performed.
Conclusions: Nasal mucosal melanoma usually has a worse prognosis than those emerging from the cutaneous sites and most patients develop recurrent and disseminated disease.


REFERENCES

  1. Ballester R, Unamuno B, Navarro M, Botella R. Actualización en melanoma mucoso. Actas Dermosifiliográficas 2015; 106 (2): 96-103. DOI: 10.1016/j.ad.2014.04.012

  2. Reynoso-Othon J, García-Iracheta F. Melanoma maligno de la mucosa nasal. An Orl Mex 2011; 56 (3): 149-152.

  3. Change AE, Karnell LH, Menck HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 1998; 83: 1664. doi: 10.1002/(sici)1097-0142(19981015)83:8<1664::aidcncr23> 3.0.co;2-g

  4. Manolidis S, Donald PJ. Malignant mucosal melanoma of the head and neck: review of the literature and report of 14 patients. Cancer 1997; 80 (8): 1373-86. doi: 10.1002/ (sici)1097-0142(19971015)80:8<1373::aid-cncr3>3.0.co;2-g

  5. Bachar G, Loh KS, O’Sullivan B, et al. Mucosal melanoma of the head and neck: experience of the Princess Margaret Hospital. Head Neck 2008; 30 (10): 1325-31. doi: 10.1002/ hed.20878

  6. Rapini RP, Golitz LE, Greer RO Jr, et al. Primary malignant melanoma of the oral cavity. A review of 177 cases. Cancer 1985; 55 (7): 1543-51. doi: 10.1002/1097-0142(19850401)55:7<1543::aid-cncr 2820550722>3.0.co;2-f

  7. Meleti M, Leemans CR, de Bree R, et al. Head and neck mucosal melanoma: experience with 42 patients, with emphasis on the role of postoperative radiotherapy. Head Neck 2008; 30 (12): 1543-51. doi: 10.1002/hed.20901

  8. Holmstrom M, Lund VJ. Malignant melanomas of the nasal cavity after occupational exposure to formaldehyde. Br J Ind Med 1991; 48 (1): 9‐11. doi: 10.1136/oem.48.1.9

  9. Cress RD, Holly EA. Incidence of cutaneous melanoma among non Hispanic whites, Hispanics, Asians, and blacks: an analysis of California cancer registry data, 1988-93. Cancer Causes Control 1997; 8 (2): 246-52. doi: 10.1023/a:1018432632528

  10. Lotem M, Anteby S, Peretz T, et al. Mucosal melanoma of the female genital tract is a multifocal disorder. Gynecol Oncol 2003; 88 (1): 45-50. https://doi.org/10.1006/ gyno.2002.6848

  11. Carvajal RD, Spencer SA, Lydiatt W. Mucosal melanoma: a clinically and biologically unique disease entity. J Natl Compr Canc Neetw 2012; 10 (3): 345-56. doi: 10.6004/ jnccn.2012.0034

  12. Stern SJ, Guillamondegui OM. Mucosal melanoma of the head and neck. Head Neck. 1991; 13 (1): 22-27. https:// doi.org/10.1002/hed.2880130104

  13. Moreno MA, Roberts DB, Kupferman ME, et al. Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center. Cancer 2010; 116: 2215. doi: 10.1002/cncr.24976

  14. Patel SG, Prasad ML, Escrig M, et al. Primary mucosal malignant melanoma of the head and neck. Head Neck 2002; 24 (3): 247‐257. doi: 10.1002/hed.10019

  15. Moctezuma-Bravo G, Díaz de León-Medina R, Rodríguez- Quilantán F, Salgado-Nevárez M, Moctezuma-Dávila M. Melanoma nasomaxilar: revisión de la literatura y reporte de un caso. Gac Mex Oncol 2016; 15 (3): 181-186. DOI: 10.1016/j.gamo.2016.04.001

  16. Roldán-Marín R, Carlos-Ortega B. Criterios dermatoscópicos para el diagnóstico de lesión melanocítica y melanoma cutáneo. Dermatología CMQ 2014; 12 (2): 142-148.

  17. Sebaratnam DF, Venugopal SS, Frew JW, et al. Diffuse melanosis cutis: a systematic review of the literature. J Am Acad Dermatol 2013; 68 (3): 482‐488. doi: 10.1016/j. jaad.2012.08.018

  18. Thompson LD, Wieneke JA, Miettinen M. Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol 2003; 27 (5): 594‐611. doi: 10.1097/00000478- 200305000-00004

  19. Ganly I, Patel SG, Singh B, et al. Craniofacial resection for malignant melanoma of the skull base: report of an international collaborative study. Arch Otolaryngol Head Neck Surg 2006; 132 (1): 73‐78. doi:10.1001/ archotol.132.1.73

  20. Ballantyne AJ. Malignant melanoma of the skin of the head and neck. An analysis of 405 cases. Am J Surg 1970; 120 (4): 425-431. https://doi.org/10.1016/S0002-9610(70)80001-0

  21. Swegal W, Koyfman Sh, Scharpf J, Sindwani R, Greskovich J, et al. Endoscopic and open surgical approaches to locally advanced sinonasal melanoma: Comparing the therapeutic benefits. JAMA Otolaryngol Head Neck Surg 2014; 140 (9): 840-845. doi: 10.1001/jamaoto.2014.1321

  22. Krengli M, Masini L, Kaanders JH, et al. Radiotherapy in the treatment of mucosal melanoma of the upper aerodigestive tract: analysis of 74 cases. A Rare Cancer Network study. Int J Radiat Oncol Biol Phys 2006; 65 (3): 751‐759. doi: 10.1016/j.ijrobp.2006.01.016

  23. Carvajal RD, Antonescu CR, Wolchok JD, et al. KIT as therapeutic target in metastasic melanoma. JAMA. 2011; 305 (22): 2327-2334. doi: 10.1001/jama.2011.746

  24. Curtin JA, Busam K, Pinkel D, Bastian BC. Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol 2006; 24 (26): 4340-6. doi: 10.1200/JCO.2006.06.2984

  25. Shoushtari AN, Munhoz RR, Kuk D, et al. The efficacy of anti-PD-1 agents in acral and mucosal melanoma. Cancer 2016; 122 (21): 3354-3362. doi: 10.1002/cncr.30259

  26. Kim KB, Sanguino AM, Hodges C, et al. Biochemotherapy in patients with metastatic anorectal mucosal melanoma. Cancer 2004; 100: 1478-1483. doi: 10.1002/cncr.20113

  27. Bartell HL, Bedikian AY, Papadopoulos NE, et al. Biochemotherapy in patients with advanced head and neck mucosal melanoma. Head Neck 2008; 30: 1592-8. doi: 10.1002/hed.20910




2020     |     www.medigraphic.com