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Revista Mexicana de Pediatría

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2002, Number 6

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Rev Mex Pediatr 2002; 69 (6)

Microbial ecology of the neonatal gastrointestinal tract

Rivera TJA
Full text How to cite this article

Language: Spanish
References: 23
Page: 257-260
PDF size: 48.72 Kb.


Key words:

Gastrointestinal tract, microbiota, microbial succession, neonate.

ABSTRACT

The gastrointestinal tract of a normal fetus is sterile. During the birth process and rapidly thereafter, microbes from the mother and surrounding environment colonize the gastrointestinal tract of the infant until a dense, complex microbiota develops. The succession of microorganisms colonizing the intestinal tract is most marked in early development, during which the feeding mode shifts from breast-feeding to formula feeding to weaning to the introduction of solid food. Dynamic balances exist between the gastrointestinal microbiota, host physiology, and diet that directly influence the initial acquisition, developmental succession, and eventual stability of the gut ecosystem. The development of the intestinal microbiota is discussed in terms of initial acquisition and subsequent succession of bacteria in infants. Intrinsic and extrinsic factors influencing microbial succession and their health significance are discussed.


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Rev Mex Pediatr. 2002;69