2020, Number 6
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Rev Fac Med UNAM 2020; 63 (6)
Rapidly Progressive Dementia, on a Creutzfeldt-Jakob Case Report
Guevara VOI, Venzor CJP, Martínez JA
Language: Spanish
References: 20
Page: 31-37
PDF size: 229.45 Kb.
ABSTRACT
The Creutzfeldt-Jakob disease is a neurodegenerative, neuroselective
and fatal entity, that is not usually reported in
Mexico. We present a 40-year-old male patient who presents
the onset of this illness, with short-term memory disorder,
depressive episodes and emotional lability with a tendency
to irritability. He also presents space disorientation, decreased
strength of the left and lateral hemibody drive in the ipsilateral
walk, and insomnia, for which he is admitted to the hospital
during 40 days for diagnostic approach. Several studies
were carried out during his hospital stay, the most relevant
for the diagnosis: a magnetic resonance which presented
"cortical ribboning" and hyperintensities in the nuclei of the
base, both diagnosis highly suggested the pathology. The
positive results to protein 14-3-3 reaffirmed the diagnosis.
After 15 months of the onset of neurological symptoms, the
patient presented symptoms of pneumonia, which lead to
the hospitalization. During his stay, he presented a pulmonary
abscess and rapid progressive dementia. The patient died in
the hospital by a pulmonary sepsis 18 months after the onset
of symptoms. No necropsy was performed, following the
current standards for the disease management.
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