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ISSN 1561-3011 (Electronic)

2020, Number 2

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Rev Cubana Invest Bioméd 2020; 39 (2)

Results of platelet concentrates in guided bone regeneration

Cruz MC, Castro-Rodríguez Y

Language: Spanish
References: 38
Page: 1-20
PDF size: 479.89 Kb.


ABSTRACT

Bone defects around dental implants are considered to be diseases affecting the support and stability of the implant, thus limiting osseointegration. Treatment of these defects involves guided bone regeneration procedures, defined as the reproduction or reconstitution of a part lost or damaged of the peri-implant bone tissue with the purpose of restoring its architecture and function. Platelet-rich plasma and fibrin-rich plasma are autologous platelet concentrates widely used in guided bone regeneration and periodontal regeneration. However, their clinical, histological and radiographic results are debated when bone defects around dental implants are dealt with.
The present review included a search for information in the databases of various search engines (PubMed, SciELO, Redalyc and ScienceDirect) to find papers about the use of platelet concentrates (platelet-rich plasma and fibrin-rich plasma) in guided bone regeneration therapy. Clinically, platelet concentrates yield favorable results in reducing probing depth and raising the level of clinical insertion in the treatment of periodontal intraosseous defects. Histologically, platelet concentrates enhance bone neoformation, speeding up regeneration. Radiographically, platelet concentrates lead to an increase in bone density, bone filler and mineralized tissue. A significant reduction is thus achieved in the size of the bone defect.


REFERENCES

  1. Preeja C, Arun S. Platelet-rich fibrin: Its role in periodontal regeneration. Saudi J Dent Res. 2014 [acceso: 12/12/2019];5:117-22. Available from: https://www.sciencedirect.com/science/article/pii/S221081571300036X

  2. Sinjab K, Garaicoa-Pazmino C, Wang HL. Decision Making for Management of Periimplant Diseases. Implant Dent. 2018 [acceso: 12/12/2019];27(3):276-81. Available from: https://insights.ovid.com/crossref?an=00008505-201806000-00006

  3. Romanos GE, Javed F, Delgado-Ruiz RA, Calvo-Guirado JL. Peri-implant diseases: a review of treatment interventions. Dent Clin North Am. 2015 [acceso: 12/12/2019];59(1):157-78. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0011-8532(14)00075-5

  4. Salgado-Peralvo A, Salgado-García A, Arriba-Fuente L. Nuevas tendencias en regeneración tisular: fibrina rica en plaquetas y leucocitos. Rev Esp Cir Oral Maxilofac. 2017 [acceso: 12/12/2019];39(2):91-8. Available from: http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S1130-05582017000200091

  5. Dohan-Ehrenfest D, Rasmusson L, Albrektsson T. Classification of platelet concentrates: From pure platelet-rich plasma (P-PRP) to leucocyte and platelet rich fibrin (L-PRF). Trends Biotechnol. 2009 [acceso: 12/12/2019];27:158-67. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0167-7799(09)00015-8

  6. Dohan-Ehrenfest D, Bielecki T, Jimbo R, Barbé G, Del Corso M, Inchingolo F et al. Do the fibrin architecture and leukocyte content influence the growth factor release of platelet concentrates? An evidence-based answer comparing a pure platelet-rich plasma (P-PRP) gel and a leukocyte- and platelet-rich fibrin (L-PRF). Curr Pharm Biotechnol. 2012 [acceso: 12/12/2019];13:1145-52. Available from: http://www.eurekaselect.com/97973/article

  7. Ding L, Tang S, Liang P, Wang C, Zhou PF, Zheng L. Bone Regeneration of Canine Peri-implant Defects Using Cell Sheets of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Fibrin Membranes. J Oral Maxillofac Surg. 2019 [acceso: 12/12/2019];77(3):499-514. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0278-2391(18)31197-2

  8. Lu J, Hao Y, Zhao W, Lyu C, Zou D. Molecular, Cellular and Pharmaceutical Aspects of Autologous Grafts for Peri-implant Hard and Soft Tissue Defects. Curr Pharm Biotechnol. 2017 [acceso: 16/12/2019];18(1):85-94. Available from: http://www.eurekaselect.com/147869/article

  9. Zhou J, Li X, Sun X, Qi M, Chi M, Yin L, et al. Bone regeneration around implant of molar teeth with autologous platelet-rich fibrin: Two case reports. Medicine (Baltimore). 2018 [acceso: 16/12/2019];97(44):e13058. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221708/

  10. Medikeri R, Meharwade V, M Wate P, V Lele S. Effect of PRF and Allograft Use on Immediate Implants at Extraction Sockets with Periapical Infection -Clinical and Cone Beam CT Findings. Bull Tokyo Dent Coll. 2018 [acceso: 16/12/2019]; 59(2):97-109. Available from: https://www.jstage.jst.go.jp/article/tdcpublication/59/2/59_2017-0021/_article

  11. Blinstein B, Bojarskas S. Efficacy of autologous platelet rich fibrin in bone augmentation and bone regeneration at extraction socket. Stomatologija. 2018 [acceso: 16/12/2019]; 20(4):111-8. Available from: https://www.ncbi.nlm.nih.gov/pubmed/?term=Efficacy+of+autologous+platelet+rich+fibrin+in+bone+augmentation+and+bone+regeneration+at+extraction+socket.+Stomatologija

  12. Suchetha A, Lakshmi P, Bhat D, Mundinamane DB, Soorya KV, Bharwani GA. Platelet concentration in platelet concentrates and periodontal regeneration-unscrambling the ambiguity. Contemp Clin Dent. 2015 [acceso: 16/12/2019];6:510-6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678550/

  13. Cortese A, Pantaleo G, Amato M, Howard C, Pedicini L, Claudio P. Platelet-rich fibrin (PRF) in implants dentistry in combination with new bone regenerative flapless technique: evolution of the technique and final results. Open Med. 2017 [acceso: 12/12/2019];12:24-32. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385970/

  14. Bansal C, Bharti V. Evaluation of efficacy of autologous platelet‑rich fibrin with demineralized‑freeze dried bone allograft in the treatment of periodontal intrabony defects. J Indian Soc Periodontol. 2013 [acceso: 16/12/2019];17(3):361-6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768188/

  15. Garg K, Srivastava R, Verma P, Gautam A, Tripathi V, Agarwal S. Clinical evaluation of platelet rich plasma when combined with an alloplastic bone graft material in the treatment of intrabony periodontal defects. Saudi J Oral Sci. 2017 [acceso: 16/12/2019];4:33-40. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768188/

  16. Sunitha J, Manjunath K. A combination of platelet rich plasma and hydroxyapatite (osteogen) bone graft in the treatment of intrabony defects – A case report: A Preliminary Study. J Clin Diagn Res. 2010 [acceso: 16/12/2019];4:2984-8. Available from: https://www.researchgate.net/publication/290693394_A_combination_of_platelet_rich_plasma_and_Hydroxyapatite_Osteogen_bone_graft_in_the_treatment_of_intrabony_defects_-_A_case_report

  17. Aghaloo T, Moy P, Freymiller E. Evaluation of platelet-rich plasma in combination with freeze-dried bone in the rabbit cranium. A pilot study. Clin Oral Impl Res. 2005 [acceso: 21/12/2019];16:250-7. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0501.2004.01075.x

  18. Chen T, Lu H, Liu G, Tang D, Zhang X, Pan Z et al. Effect of Autologous Platelet Rich Plasma in Combination With Bovine Porous Bone Mineral and Bio-Guide Membrane on Bone Regeneration in Mandible Bicortical Bony Defects. J Craniofac Surg. 2014 [acceso: 21/12/2019];25:215-23. Available from: https://insights.ovid.com/pubmed?pmid=24406581

  19. Papli R, Chen S. Surgical Treatment of Infrabony Defects With Autologous Platelet Concentrate or Bioabsorbable Barrier Membrane: A Prospective Case Series. J Periodontol. 2007 [acceso: 21/12/2019];78:185-93. Available from: https://aap.onlinelibrary.wiley.com/doi/abs/10.1902/jop.2007.060052

  20. Taneja N, Kudva P, Goswamy M, Bhat G, Kudva H. A comparative evaluation of platelet‑rich fibrin with metronidazole and platelet‑rich fibrin alone in the treatment of intrabony periodontal defects: A clinical and radiographical study. J Interdiscip Dentistry. 2017 [acceso: 21/12/2019];7:101-10. Available from: https://www.researchgate.net/publication/322111709_A_Comparative_evaluation_of_platelet-rich_fibrin_with_metronidazole_and_platelet-rich_fibrin_alone_in_the_treatment_of_intrabony_periodontal_defects_A_clinical_and_radiographical_study

  21. Elgendy E, Shady T. Clinical and radiographic evaluation of nanocrystalline hydroxyapatite with or without platelet‑rich fibrin membrane in the treatment of periodontal intrabony defects. J Indian Soc Periodontol. 2015 [acceso: 21/12/2019];19(1):61-5. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365160/

  22. Pradeep A, Shetty S, Garg G, Pai S. Clinical Effectiveness of Autologous Platelet Rich Plasma and Peptide-Enhanced Bone Graft in the Treatment of Intrabony Defects. J Periodontol. 2009 [acceso: 21/12/2019]; 80(1):62-71. Available from: https://aap.onlinelibrary.wiley.com/doi/abs/10.1902/jop.2009.080214

  23. Agarwal P, Chatterjee A, Gokhale S, Singh H, Kandwal A. Evaluation of platelet -rich plasma alone or in combination with demineralized freeze dried bone allograft in treatment of periodontal infrabony defects: A comparative clinical trial. J Indian Soc Periodontol. 2016 [acceso: 03/01/2020];20:42-7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795133/

  24. Camargo P, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney E. Platelet-rich plasma and bovine porous bone mineral combined with guided tissue regeneration in the treatment of intrabony defects in humans. J Periodont Res. 2002 [acceso: 03/01/2020];37:300-6. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1034/j.1600-0765.2002.01001.x?sid=nlm%3Apubmed

  25. Sánchez-Gutiérrez C, Cepeda-Bravo J, Fierro-Serna V, García-García C, Martínez-Rider R, Noyola-Frías M. Eficacia del uso del plasma rico en factores de crecimiento en defectos periodontales distales de segundos molares inferiores, posterior a la extracción de un tercer molar mandibular. Rev Esp Cir Oral Maxilofac. 2017 [acceso: 03/01/2020];39(3):164-70. Available from: https://pesquisa.bvsalud.org/portal/resource/pt/ibc-164263

  26. Oktay E, Demiralp B, Demiralp B, Senel S, Akman A, Eratalay K et al. Effects of Platelet-Rich Plasma and Chitosan Combination on Bone Regeneration in Experimental Rabbit Cranial Defects. J Oral Implantol. 2010 [acceso: 03/01/2020];36(3):175-84. Available from: https://www.joionline.org/doi/10.1563/AAID-JOI-D-09-00023?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

  27. Paknejad M, Shayesteh Y, Yaghobee S, Shariat S, Dehghan M, Motahari P. Evaluation of the Effect of Plasma Rich in Growth Factors (PRGF) on Bone Regeneration. J Dent. 2012 [acceso: 03/01/2020]; 9(1):59-67. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422064/

  28. Jeon Y, Kim M, Kim Y, Roh T, Lee W, Kang E et al. Scaffold Free Bone Regeneration Using Platelet-Rich Fibrin in Calvarial Defect Model. J Craniofac Surg. 2017 [acceso: 03/01/2020]; 29(1):251-4. Available from: https://insights.ovid.com/pubmed?pmid=29215443

  29. Garcia R, Cabrini M, Hochuli-Vieira E, Spolidorio L, Padilha J, Doria F et al. Effect of Platelet-Rich Plasma on Peri-Implant Bone Repair: A Histologic Study in Dogs. J Oral Implantol. 2010 [acceso: 03/01/2020];36(4):281-90. Available from: https://www.joionline.org/doi/10.1563/AAID-JOI-D-09-00056?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

  30. Durmuslar M, Balli U, Dede F, Misir A, Baris E, Kurkcu M et al. Histological Evaluation of the Effect of Concentrated Growth Factor on Bone Healing. J Craniofac Surg. 2016 [acceso: 03/01/2020];27:1494-7. Available from: https://insights.ovid.com/pubmed?pmid=27428921

  31. Seyhan N, Keskin S, Aktan M, Avunduk M, Sengelen M, Savaci N. Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects. J Craniofac Surg. 2016 [acceso: 05/01/2020];27:1367-70. Available from: https://insights.ovid.com/pubmed?pmid=27300463

  32. Sindel A, Dereci O, Toru H, Tozoglu S. Histomorphometric Comparison of Bone Regeneration in Critical-Sized Bone Defects Using Demineralized Bone Matrix, Platelet-Rich Fibrin, and Hyaluronic Acid as Bone Substitutes. J Craniofac Surg. 2017 [acceso: 05/01/2020];00(00):1-4. Available from: https://insights.ovid.com/pubmed?pmid=28358761

  33. Rocha F, Ramos L, Batista J, Zanetta-Barbosa D, Vieira E, Dechichi P. Bovine Anorganic Bone Graft Associated with Platelet-Rich Plasma: Histologic Analysis in Rabbit Calvaria. J Oral Implantol. 2011 [acceso: 05/01/2020];37(5):511-8. Available from: https://www.joionline.org/doi/10.1563/AAID-JOI-D-09-00091.1?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

  34. Wiltfang J, Kloss F, Kessler P, Nkenke E, Schultze-Mosgau S, Zimmermann R et al. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects. An animal experiment. Clin Oral Impl Res. 2004 [acceso: 05/01/2020];15:187-93. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0501.2004.00980.x?sid=nlm%3Apubmed

  35. Özdemir B, Kurtis B, Tuter G, Şenguven B, Yildirim B, Özcan G. Osteocalcin and osteonectin expression after double application of platelet-rich plasma in rabbits. J Istanbul Univ Fac Dent. 2016 [acceso: 05/01/2020];50(2):1-9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573525/

  36. Chakar C, Naaman N, Soffer E, Cohen N, Osta N, Petite H. Bone Formation with Deproteinized Bovine Bone Mineral or Biphasic Calcium Phosphate in the Presence of Autologous Platelet Lysate: Comparative Investigation in Rabbit. Int J Biomater. 2014 [acceso: 05/01/2020];1-10. Available from: https://www.researchgate.net/publication/262972597_Bone_Formation_with_Deproteinized_Bovine_Bone_Mineral_or_Biphasic_Calcium_Phosphate_in_the_Presence_of_Autologous_Platelet_Lysate_Comparative_Investigation_in_Rabbit-_Research_Article

  37. Messora M, Nagata M, Fucini S, Pola N, Campos N, De Oliveira G et al. Effect of Platelet-Rich Plasma on the Healing of Mandibular Defects Treated With Fresh Frozen Bone Allograft: A Radiographic Study in Dogs. J Oral Implantol. 2014 [acceso: 05/01/2020];40(5):533-41. Available from: https://www.joionline.org/doi/10.1563/AAID-JOI-D-12-00175?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

  38. Jeon Y, Jung B, Roh T, Kang E, Lee W, Rah D et al. Comparing the Effect of Nonactivated Platelet-Rich Plasma, Activated Platelet-Rich Plasma, and Bone Morphogenetic Protein-2 on Calvarial Bone Regeneration. J Craniofac Surg. 2016 [acceso: 05/01/2020];27:317-21. Available from: https://insights.ovid.com/pubmed?pmid=26967070




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