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Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 12

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Ginecol Obstet Mex 2020; 88 (12)

Vitamin D levels in pregnant women and their relationship with gestational diabetes

Collantes-Gutiérrez AA, Romero-Ogawa T, Morales-López A, Espinosa-de Santillana IA

Language: Spanish
References: 27
Page: 853-859
PDF size: 192.56 Kb.


ABSTRACT

Objective: Contrast the levels of vitamin D, in pregnant woman with and without gestational diabetes.
Material and Method: This was an prospective, case control study, were we compared vitamin D levels between two groups, 25 pregnant women with gestational diabetes and, paired by age and IMC, with 25 healthy pregnant control women, who attended to prenatal care, in the department of Gynecology and Obstetrics in the Hospital Universitario de Puebla.
Results: Regardless of gestational diabetes, vitamin D deficiency was in 30% patients, and vitamin D insufficiency in the 44%. The vitamin D levels between the patients with gestational diabetes (23.29 ± 9.00 ng/mL) and the healthy patients (26.76 ± 9.33 ng/ mL), didn’t show significant difference (p = 0.14). This study didn’t show association between gestational diabetes and vitamin D deficiency OR = 1.882 (IC95%: 0.518- 6.845; p = 0.333).
Conclusions: Vitamin D levels didn’t relate to gestational diabetes. Pregnant women had high percentages of vitamin D deficiency and insufficiency.


REFERENCES

  1. American Diabetes Association. Classification and diagnosis of diabetes. Diabetes Care. 2017; 40:S11-S24. doi.10.2337/ dc17-S005

  2. Instituto Mexicano del Seguro Social. Diagnóstico y tratamiento de la diabetes en el embarazo. 2016:1-68. http:// www.imss.gob.mx/sites/all/statics/guiasclinicas/320GER. pdf.

  3. Bello-Chavolla OY, et al. Epidemiology of diabetes mellitus in Mexico. Nutr Rev. 2017; 75: 4-12. doi.10.1093/nutrit/ nuw030

  4. Serrano Berrones MA. Incidencia de diabetes gestacional en el Hospital Regional Adolfo López Mateos mediante la prueba de O´Sullivan. Rev Esp Méd Quir. 2013; 18: 287-91.

  5. Ramírez-Torres MA. The importance of gestational diabetes beyond pregnancy. Nutr Rev. 2013; 71 (Suppl 1): 37-41. doi.10.1111/nure.12070

  6. Savitz DA, et al. Ethnicity and gestational diabetes in New York City, 1995-2003. BJOG An Int J Obstet Gynaecol. 2008; 115 (8): 969-78. doi.10.1111/j.1471-0528.2008.01763.x

  7. Mousa A, et al. Relationship between vitamin D and gestational diabetes in overweight or obese pregnant women may be mediated by adiponectin. Mol Nutr Food Res. 2017:1700488. doi.10.1002/mnfr.201700488

  8. Pons R, et al. Risk factors for gestational diabetes mellitus in a sample of pregnant women diagnosed with the disease. Diabetol Metab Syndr. 2015; 7 (Suppl 1): A80. doi.10.1186/1758-5996-7-S1-A80

  9. Huerta-Chagoya A, et al. Genetic determinants for gestational diabetes mellitus and related metabolic traits in mexican women. PLoS One. 2015; 10 (5): 1-17. doi.10.5061/ dryad.kq0k2.The

  10. Amraei M, et al. Effects of vitamin d deficiency on incidence risk of gestational diabetes mellitus: A systematic review and meta-analysis. Front Endocrinol (Lausanne). 2018; 9: 7. doi.10.3389/fendo.2018.00007

  11. Al-Shaikh GK, et al. Impact of vitamin D deficiency on maternal and birth outcomes in the Saudi population: A cross-sectional study. BMC Pregnancy Childbirth. 2016; 16 (1): 1-9. doi.10.1186/s12884-016-0901-4

  12. Dovnik A, Mujezinović F. The association of vitamin D levels with common pregnancy complications. Nutrients. 2018; 10 (7): 867. doi.10.3390/nu10070867

  13. Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014; 21 (3): 319-29. doi.10.1016/j.chembiol.2013.12.016

  14. Triunfo S, et al. Low maternal circulating levels of vitamin D as potential determinant in the development of gestational diabetes mellitus. J Endocrinol Invest. 2017; 40 (10): 1049- 59. doi.10.1007/s40618-017-0696-9

  15. González-Parra E, Egido J. Vitamina D, síndrome metabólico y diabetes mellitus. Med Clin (Barc). 2014; 142 (11): 493-96. doi.10.1016/j.medcli.2014.01.024

  16. Zhang Y, et al. Vitamin D and gestational diabetes mellitus: a systematic review based on data free of Hawthorne effect. BJOG An Int J Obstet Gynaecol. 2018; 125 (7): 784-93. doi.10.1111/1471-0528.15060

  17. Aghajafari F, et al. Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies. BMJ 2013; 346: f1169. doi.10.1136/bmj.f1169

  18. Dabelea D, et al. Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM screening program. Diabetes Care. 2005; 28 (3): 579-84. doi.10.2337/diacare. 28.3.579

  19. Bener A, et al. Prevalence of gestational diabetes and associated maternal and neonatal complications in a fastdeveloping community: global comparisons. Int J Womens Health. 2011; 3: 367-73. doi.10.2147/IJWH.S26094

  20. Shamah-Levy T, et al. Overweight and obesity in Mexican vulnerable population. Results of Ensanut 100k. Salud Publica Mex. 2019; 61 (6): 852-65. doi.10.21149/10585

  21. Medina C, et al. Evidence of increasing sedentarism in Mexico City during the last decade: Sitting time prevalence, trends, and associations with obesity and diabetes. PLoS One. 2017; 12 (12). doi.10.1371/journal. pone.0188518

  22. Dodds L, et al. Vitamin D status and gestational diabetes: Effect of smoking status during pregnancy. Paediatr Perinat Epidemiol. 2016; 30 (3): 229-37. doi.10.1111/ ppe.12278

  23. De-Regil LM, et al. Vitamin D supplementation for women during pregnancy. Sao Paulo Med J. 2016; 134 (3): 274-75. doi.10.1590/1516-3180.20161343T2

  24. Holick MF, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 1911; 96 (7): 1911-30. doi.10.1210/jc.2011-0385

  25. Rodriguez A, et al. Associations of maternal circulating 25-hydroxyvitamin D3 concentration with pregnancy and birth outcomes. BJOG An Int J Obstet Gynaecol. 2015; 122 (12): 1695-704. doi.10.1111/1471-0528.13074

  26. Fard BB. Comparison of vitamin D level in pregnant women with and without gestational diabetes. Rev Latinoam Hipertens. 2020; 15: 33-35. www.revhipertension.com.

  27. Camarena-Pulido EE, et al. Concentraciones de 25-hidroxivitamina D en mujeres embarazadas con y sin diabetes gestacional. Ginecol Obstet Mex. 2018; 86 (10): 658-64. doi.10.24245/gom.v86i10.2262




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