medigraphic.com
Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 12

<< Back Next >>

Ginecol Obstet Mex 2020; 88 (12)

Usefulness of feto-placental pulsed Doppler assessment in placental mesenchymal dysplasia: case report and literature review

Medina-Castro N, Rivas-García JA, Herrera-Cifuentes SL, Velázquez-Olguín JG, Medina-Castro D

Language: Spanish
References: 21
Page: 897-904
PDF size: 285.71 Kb.


ABSTRACT

Background: Placental mesenchymal dysplasia (PMD) is a rare condition of recent description, often mistaken with other placental diseases. PMD is associated to fetal anomalies and syndromes. However, some fetuses are anatomically and genetically normal.
Clinic case: Patient is 29 years old, with a history of 4 pregnancies, two cesarean sections and one abortion. In the first trimester of pregnancy, placental mesenchymal dysplasia was diagnosed and evaluated with serial Doppler of the uterine, umbilical and middle cerebral arteries. As these are exceptional cases, a brief bibliographic review is made.
Conclusions: Placental mesenchymal dysplasia has a wide spectrum of clinical behavior. For fetuses without abnormalities there are no clear guidelines about fetal surveillance. We suggest a serial evaluation of fetal well-being that includes, but is not restricted to, maternal-fetal Doppler evaluation and cardiotocographic recording, among other biophysical variables, since they have a high risk of unexplained death.


REFERENCES

  1. Takayama M, et al. Abnormally large placenta associated with Beckwith-Wiedemann syndrome. Gynecol Obstet Invest. 1986; 22: 165-8. doi. 10.1159/000298909

  2. Moscoso G, Jauniaux E. Placental vascular anomaly with diffuse mesenchymal stem villous hyperplasia: new clinicpathological entity? Pathol Res Pract 1991; 187: 324-8. doi. 10.1016/S0344-0338(11)80791-0

  3. Woo G, et al. Placental mesenchymal dysplasia. Am J Obstet Gynecol 2011; e3-e5. doi. 10.1016/j.ajog.2011.08.019

  4. Guenot C, et al. Placental mesenchymal dysplasia: An underdiagnosed placental pathology with various clinical outcomes. Eur J Obstet Gynecol Reprod Biol. 2019; 234: 155-64. doi. 10.1016/j.ejogrb.2019.01.014.

  5. Nayeri UA, et al. Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 2013; 41 (4): 366-74. doi. 10.1002/uog.12359.

  6. Simeone S, et al. Management of placental mesenchymal dysplasia associated with fetal anemia and IUGR. Eur J Obstet Gynecol Reprod Biol. 2015; 184: 132-4. doi: 10.1016/j. ejogrb.2014.09.024.

  7. Jauniaux E, et al. Perinatal features associated with placental mesenchymal dysplasia. Placenta. 1997; 18 (8): 701-6. doi. 10.1016/s0143-4004(97)90012-6.

  8. Sudano MC, et al. Placental mesenchymal dysplasia, a case of intrauterine sudden death in a normal-sized fetus. J Prenat Med. 2013; 7 (1): 9-11. doi. 10.11138/ jpm/2013.7.1.009

  9. Medina Castro N, et al. Valores de referencia del índice de pulsatilidad de las arterias uterina y umbilical durante el embarazo. Ginecol Obstet Mex 2006; 74: 504-15.

  10. Medina Castro N, et al. Valores de referencia del índice de pulsatilidad y velocidad máxima en la arteria cerebral media fetal durante el embarazo normal. Ginecol Obstet Mex 2006; 74: 376-82.

  11. Pham T, et al. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 2006; 126 (1): 67-78. doi. 10.1309/RV45-HRD5-3YQ2-YFTP.

  12. Álvarez-Silvares E, et al. Displasia mesenquimal de placenta: revisión sistemática. Ginecol Obstet Mex. 2018; 86 (1): 70-83. http://dx.doi.org/10.24245/gom.v86i1.1704

  13. Gheysen W, et al. Discordance for placental mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy: A case report. Clin Case Rep. 2018; 6 (8): 1557-1560. doi: 10.1002/ccr3.1662.

  14. Doroftei B, et al. A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction. Medicine (Baltimore). 2019; 98 (8): e14554. doi: 10.1097/MD.0000000000014554.

  15. Psarris A, et al. Placental Mesenchymal Dysplasia: Ultrasound Characteristics and Diagnostic Pitfalls. Ultrasound Int Open. 2020; 6 (1): E2-E3. doi: 10.1055/a-1180-9571.

  16. Ishikawa S, et al. Prospective risk of stillbirth in women with placental mesenchymal dysplasia. J Obstet Gynaecol Res. 2015; 41 (10): 1562-8. doi: 10.1111/jog.12757.

  17. Kuwabara Y, et al. Unique Clinical and Histological Features of Placental Mesenchymal Dysplasia Complicated by Severe Preeclampsia in the Midtrimester. AJP Rep. 2020; 10 (1): e113-e117. doi: 10.1055/s-0040-1709186.

  18. Yamada A, et al. Placental mesenchymal dysplasia, a case of intrauterine sudden death. Kobe J Med Sci. 2014; 60 (1): E1-4. http://www.med.kobe-u.ac.jp/journal/contents/60/ E1.pdf.

  19. Gerli S, et al. Early ultrasonographic diagnosis of placental mesenchymal dysplasia. Eur Rev Med Pharmacol Sci. 2014; 18 (17): 2419-23. http://dx.doi.org/10.1016/j. ejogrb.2014.09.024.

  20. Oide S, et al. Placental mesenchymal dysplasia with a good outcome: A case report. J Obstet Gynaecol Res. 2019; 45 (11): 2284-88. doi: 10.1111/jog.14095.

  21. Colpaert RM, et al. Diagnosis and Management of Placental Mesenchymal Disease. A Review of the Literature. Obstet Gynecol Surv. 2019; 74 (10): 611-622. doi: 10.1097/ OGX.0000000000000716.




2020     |     www.medigraphic.com