medigraphic.com
SPANISH

Acta Médica Grupo Angeles

Órgano Oficial del Hospital Angeles Health System
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
    • Names and affiliations of the Editorial Board
  • Policies
  • About us
    • Data sharing policy
    • Stated aims and scope
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 4

<< Back Next >>

Acta Med 2020; 18 (4)

Parenteral paraquat poisoning

Fuentes MDA, del Real RR, Peña EM, Canizales RJA, Juárez SCA
Full text How to cite this article 10.35366/97269

DOI

DOI: 10.35366/97269
URL: https://dx.doi.org/10.35366/97269

Language: Spanish
References: 13
Page: 411-413
PDF size: 120.00 Kb.


Key words:

Paraquat, poisoning, suicide, pulmonary fibrosis.

ABSTRACT

Herbicides are agricultural products widely distributed worldwide. Paraquat (1,1’-dimethyl-4,4’-bipyridyl) is a potent bipyridyl-type herbicide and desiccant, which is available as a 20% standard solution. In Mexico, it is still highly used despite attempts to restrict it. Due to its high lethality, it is used for suicide purposes. The main route of administration is the gastrointestinal route, although some cases have been reported intravenously, intramuscularly and intradermally. Parenteral paraquat poisoning is extremely rare and is associated in most cases with suicide attempt. We present the case of a 13-year-old female, who self-administered paraquat intramuscularly and who developed lethal complications as a consequence of intoxication by said product, whose death occurred 20 days after administration of paraquat.


REFERENCES

  1. Bejarano-González F. Los plaguicidas altamente peligrosos: nuevo tema normativo internacional y su perfil nacional en México. En: Bejarano-González F. Los plaguicidas altamente peligrosos en México. Primera edición. México: Red de Acción sobre Plaguicidas y Alternativas en México, A. C. 2017; pp. 13-138.

  2. Raghu K, Mahesh V, Sasidhar P, Reddy PR, Venkataramaniah V, Agrawal A. Paraquat poisoning: a case report and review of literature. J Fam Community Med. 2013; 20: 198-200.

  3. Viales-López G. Intoxicación por paraquat. Medicina Leg Costa Rica. 2014; 31 (2): 88-94.

  4. Marín-Cuartas M, Berrouet-Mejía MC. Intoxicación por paraquat. Rev CES Med. 2016; 30 (1): 114-121.

  5. Hernández J, Contreras-Zúñiga E, Zuluaga-Martínez S. Intoxicación por paraquat: descripción de un caso clínico. Acta Toxicol Argent. 2008; 16 (1): 5-8.

  6. Harley JB, Grinspan S, Root RK. Paraquat suicide in a young woman: results of therapy directed against the superoxide radical. Yale J Biol Med. 1977; 50 (5): 481-488.

  7. Lim SW, Lee WY, Han HS, Hahn JS, Kim MO, Kwon SK et al. A case of paraquat intoxication caused by intramuscular injection. Korean J Nephrol. 2004; 23: 505-508.

  8. Gheshlaghi F, Eizadi-Mood N, Mohammad SA, Mahdy MS. Intramuscular injection of paraquat for suicidal attempt: a rare case report. Clin Toxicol. 2012; 50 (4): 270.

  9. Caridad A, López Menchero R, Maduell F, Sigüenza F. Intoxicación con paraquat por vía parenteral. Nefrología. 1994; 14 (6): 707-710.

  10. Ramirez SM, Bastidas O, Mujica Y, Pacheco FJ, Gómez PN, Abello MI. Intoxicación pediátrica por paraquat (Gramoxone). Supervivencia en dos casos. Archivos Venezolanos de Puericultura y Pediatría. 2010; 73 (1): 20-26.

  11. Cartagena S, Díaz I, Gutiérrez C et al. Fibrosis pulmonar aguda asociada a intoxicación por paraquat: caso clínico. Rev Med Chile. 2018; 146: 938-941.

  12. Nogué S, Munné P, Campañá E, Bertrán A, Reig R, Rodamilans M. Failure of a cyclophosphamide-dexamethasone combination in paraquat. Medicina Clínica. 1989; 2: 61-63.

  13. Moreno-Rivillo M, Salinas-Aguilera R, Troncoso-Acuña J. Intoxicación severa por paraquat: a propósito de un caso. Revista Chilena de Medicina Intensiva. 2016; 31 (1): 27-30.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Acta Med. 2020;18