medigraphic.com
SPANISH

Revista Cubana de Medicina

ISSN 1561-302X (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2019, Number 4

<< Back Next >>

Rev cubana med 2019; 58 (4)

Validation of neutrophil/lymphocyte index predictive of severity in the surgical cancer patient

Fuentes DZ, Rodríguez SO, Chamizo RC, Puerto PT
Full text How to cite this article

Language: Spanish
References: 10
Page: 1-10
PDF size: 339.76 Kb.


Key words:

neutrophil/lymphocyte index, cancer, prediction.

ABSTRACT

Introduction: Inflammation plays a leading role in the pathophysiology of cancer. Objective: To validate the predictive severity neutrophil/lymphocyte index in the elective surgical oncology patient.
Methods: A quasi-experimental study was carried out for a single group in surgical patients diagnosed with oncological disease, electively operated by the different surgical specialties at Marie Curie Cancer Hospital from January to December 2019.
Results: The Receiver Operating Characteristic curve was associated with the logistic regression model as it estimates the threshold of 0.23 above which the probability of severity will be declared. In the validation among the patients, there are 23 who did have a serious risk. These are the false positives on which the preoperative period was optimized.
Conclusions: The neutrophil/lymphocyte index showed utility in predicting severity in the surgical oncology patient, and made it possible to individualize the pre-surgical treatment so that it would be more successful.


REFERENCES

  1. Zahorec R. Ratio of neutrophil to lymphocyte counts/rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102:5-14.

  2. Fleisher L, Wiener-Kronish J. Panorama general de la anestesia. In Goldman L, Shaffer AI, Arnold R, Taylor VM, Shroeder SA, Schriger DL, et al. Tratado de Medicina Interna. New York: McGraw-Hill; 2016 .p. 2487-96.

  3. Tang H, Lu W, Li B, Li C, Xu Y, Dong J. Prognostic significance of neutrophil-tolymphocyte ratio in biliary tract cancers: a systematic review and meta-analysis. Oncotarget. 2017[acceso: 23/10/2019];8(22):36857-68. Disponible en: http://www.impactjournals.com

  4. Mille Loera JE, Cuellar Guzmán LF, Alvarado Pérez J, García Velasco O, Fabela Barragán JA. Anestesia en el paciente oncológico. Revista Mexicana de Anestesiología. 2017[acceso: 23/10/2019];40(supl. 1):132-34. Disponible en: http://www.medigraphic.org.mx

  5. Reyes Gálvez JA, Gracida Mancilla NI, Enríquez Santos D, Carrillo Esper R. Índice neutrófilos-linfocitos como predictor de gravedad y mortalidad en pacientes con sepsis abdominal. Med Int Mex. 2016[acceso: 23/10/2019];32(1):41-47. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=64340

  6. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001[acceso: 23/10/2019];357:539-45. Disponible en https://www.sciencedirect.com/science/article/pii/S0140673600040460?via%3Dihub

  7. Sarraf KM, Belcher E, Raevsky E, Nicholson AG, Goldstraw P, Lim E. Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J Thorac Cardiovasc Surg. 2009[acceso: 23/10/2019];137;(2):425-8. Disponible en: https://www.clinicalkey.es/#!/content/playContent/1-s2.0- F

  8. Martínez Urbistondo D, Beltrán A, Beloqui O, Huerta A. El índice neutrófilo/linfocito como marcador de disfunción sistémica endotelial en sujetos asintomáticos. Nefrología. 2016[acceso: 23/10/2019];36(4):397-403. Disponible en: https://www.revistanefrologia.com/es-el-indice-neutrofilo-linfocito-como-marcadorarticulo- S0211699515002246

  9. Walsh SR, Cook EJ, Goulder F, Justin TA, Keeling NJ. Neutrophil ymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol. 2005;91(3):181-4. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/16118772

  10. Halazun KJ, Aldoori A, Malik HZ, Al-Mukhtar A, Prasaid KR, Toogood GJ, et al. Elevated preoperative neutrophil to lymphocyte ratio predicts survival following hepatic resection for colorectal liver metastases. Eur J Surg Oncol. 2008[acceso: 23/10/2019];34:55-60. Disponible en: https://www.clinicalkey.es/#!/content/playContent/1-s2.0-S0748798307000789?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0748798307000789%3Fshowall%3Dtrue&referrer=https:%2F%2Fwww.ncbi.nlm.nih.gov%2F




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev cubana med. 2019;58