González-Alamilla E, Rivas-Jacobo M, Sosa-Gutiérrez C, Delgadillo-Ruiz L, Valladares-Carranza B, Rosenfeld-Miranda C, Zaragoza-Bastida A, Rivero-Pérez N

Language: Spanish
References: 21
Page: 1-11
PDF size: 692.52 Kb.

ABSTRACT

The excessive use of antibiotics, has generated resistance of microorganisms to these, have been searched effectives alternatives for treating diseases caused by resistant or multiresistant microorganism, within of these alternatives are plants, which by its content of secondary compounds have antibacterial activity. The aim on the present experiment was characterize and determine the antibacterial activity of methanolic extract of Salix babylonica (SB) against important bacteria in public health. To obtain extract, the maceration technique was used, qualitative and quantitative (gas chromatography) chemical characterization was carried. For antibacterial activity, the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) was determined, the characterization of the extract allowed the identification of phenolic compounds, coumarins, lactones, flavonols, quinones, saponins, triterpenes and steroidal compounds, also Thymol (0.5319 mg/mL) and Carvacrol (0.4158 mg/mL). The extract showed the best activity against Bacillus. subtilis (MIC: 12.5 mg/mL and WBC: 25 mg/mL), Listeria. monocytogenes and Staphylococcus. aureus (MIC: 25 mg/mL and MBC: 50 mg/mL). It is concluded that the methanolic extract of SB can be an alternative for the treatment of diseases produced by resistant or multiresistant bacteria to antibiotics.

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