Solano-Anguiano Ó, Navarrete-Solís J, Peña-Ruelas C, Hernández-Martínez S

Language: Spanish
References: 12
Page: 292-295
PDF size: 640.48 Kb.

ABSTRACT

The primary cutaneous anaplastic large cell lymphoma CD30+ is characterized by the presence of atypical T lymphocytes that express CD30; they present with solitary, grouped or multifocal erythematous-brown nodules that present tendency to ulceration. Histopathologically, a nodular infiltrate of large lymphoid cells expressing CD2, CD4 or CD8, CD45RO and by definition CD30 must be positive in more than 75%. The use of local radiotherapy or surgical excision can be chosen, the option of chemotherapy with multiple agents offers a cure rate of up to 85% with chop. The most current treatment available is brentuximab vedotin, an anti CD30.
Actinomycosis is a polymicrobial infection, Actinomyces israelii is the main cause in the cervico-facial form, produces masses with the presence of fistulas, the diagnosis is based on histological characteristics with filamentous structures and characteristic grains, penicillin or other beta-lactams are an option of treatment for the presented susceptibility. Next, we present the case of a patient with primary cutaneous lymphoma of large CD30+ cells that has an association with actinomycosis, the approach, treatment and evolution.

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