Pereira-Cabeza JD, Valencia-Núñez LV, García-Perdomo HA

Language: English
References: 5
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In December 2019, in the province of Hubei (Wuhan-China), there was an outbreak of a coronavirus-associated pneumonia, called coronavirus disease 2019 (COVID 19). SARS-CoV-2 enters the cell by angiotensin-converting enzyme 2 (ECA 2) receptors that are expressed in multiple organs, including testicular tissue. Protein S is most likely primed by transmembrane serine protease 2 (TMPRSS2), which interacts with ACE receptors, resulting in the successful entry of the virus into the cell.
Respiratory and gastrointestinal symptoms of the disease were the first to be described but some authors reported testicular discomfort in cases of acute infection. Aerosols and contact are the main transmission routes of this virus; however, SARS-CoV-2 has been found to be present in semen samples from COVID-19-positive patients and those in recovery.

REFERENCES

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2. Holtmann N, Edimiris P, Andree M, Doehmen C, Baston-Buest D, Adams O, et al. Assessment of SARS-CoV-2 in human semen—a cohort study. Fertil Steril. 2020 Aug;114(2):233– 8. doi: https://dx.doi.org/10.1016%2Fj. fertnstert.2020.05.028

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