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2021, Number 2

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salud publica mex 2021; 63 (2)

Markers of kidney function among SARS-CoV-2 infected patients. A rapid review of the literature.

Salazar-Martínez E, Hernández-Mariano JÁ, Galván-Portillo M, Baltazar-Reyes MC, Parra-Cabrera MS, Tamayo y Orozco JA, Cupul-Uicab LA
Full text How to cite this article

Language: Spanish
References: 61
Page: 253-261
PDF size: 377.19 Kb.


Key words:

SARS-CoV-2, chronic kidney disease, acute kidney injury, comorbidity, renal biomarkers.

ABSTRACT

Objective. To summarize the scientific literature on kidney abnormalities associated with SARS-CoV-2 infection. Materials and methods. It was conducted a rapid review using the Cochrane methodology. Results. Pre-existing chronic kidney disease (CKD) in SARS-CoV-2 infected patients ranged from 1-38% and acute kidney injury (AKI) ranged from 2.9- 86.4%. The prognosis of patients with SARS-CoV-2 infection was worse among those with CKD and those with normal remnant kidney function (RKF) that developed AKI. The risk of death was higher (pooled risk ratio =1.49; 95%CI: 1.09- 2.04) among SARS-CoV-2 infected patients with pre-existing CKD. The RKF markers showed alterations among severe and non-surviving SARS-CoV-2 patients; the most common marker was serum creatinine. Conclusions. The scientific evidence shows the relevance of the evaluation and permanent monitoring of the RKF in SARS-CoV-2 hospitalized patients to improve the prognosis of those with pre-existing CKD as well as the prognosis of those without CKD who develop AKI.


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