medigraphic.com
SPANISH

MediSan

ISSN 1029-3019 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 04

<< Back Next >>

MediSan 2020; 24 (04)

Seric albumin as prediction factor of multiple failures of organs in patients with secondary diffuse peritonitis

González AJC, Cabrera LJO, Martí GGM, Pérez AME
Full text How to cite this article

Language: Spanish
References: 20
Page: 627-640
PDF size: 1239.91 Kb.


Key words:

seric albumin, peritonitis, multiorganic failure, prediction factor, mortality due to peritonitis, intensive cares unit.

ABSTRACT

Introduction: Seric albumin constitutes one of the parameters used to predict the risk of complications in patients surgically intervened.
Objective: To evaluate the utility of seric albumin as prediction factor of multiple failure of organs in patients with secondary diffuse peritonitis.
Method: An observational, cohorts analytic study of 54 patients with secondary diffuse peritonitis was carried out, they were assisted in the Intensive Cares Unit of Carlos Manuel de Céspedes University General Hospital in Bayamo, Granma, during 2016. The marker variable of prediction was the multiple failures of organs that was evaluated with the Sequential scale Organ Failure Assessment.
Results: In the 37.7 % of patients multiple failure of organs was developed; also, the average value of seric albumin at admission (standard deviation) was 30.3 g/L (+ 3.4) in patients with this disorder and 33.2 g/L (+ 4.1) without this disorder (p=0.012). The relative risk of multiple failure of organs was 1.9 (CI: 95 % 1.1-3.2) with albumin of 30 g/L or less. In the multivariate analysis seric albumin constituted an independent factor of multiple failure of organs along with APACHE II index; while the area under the curve receiving operator presented a value of 0.7 when the discriminative capacity of the albumin was considered to predict if the multiple failure of organs was not present and 0.2 to predict its development.
Conclusions: Seric albumin is useful as prediction factor of multiple failure of organs in patients with secondary diffuse peritonitis.


REFERENCES

  1. 1.van Ruler O, Boermeester MA. Surgical treatment of secondary peritonitis. A continuing problem. Chirurg. 2017 [citado 28/12/2019]; 88 (Suppl 1):S1–S6. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26746213/

  2. Ballus J, López JC, Sabater J, Perez XL, Betbese AJ, Roncal JA. Surgical site infection in critically ill patients with secondary and tertiary peritonitis: epidemiology, microbiology and influence in outcomes. BMC Infec Dis. 2015 [citado 28/12/2019];15:304-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520265/pdf/12879_2015_Article_1050.pdf

  3. Rodríguez ET, González JC, Cabrera JO, Algas LA. Factores pronósticos de fallo orgánico y muerte en pacientes con peritonitis difusa secundaria. Rev Cubana Med Intens Emerg. 2018 [citado 28/12/2019]; 17(4):1-18. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/424/601

  4. Sanjay Nag D. Assessing the risk: Scoring systems for outcome prediction in emergency laparotomies. Biomedicine (Taipei). 2015 [citado 28/12/2019]; 5(4):20. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26615537/

  5. Tridente A, Clarke GM, Walden A, Gordon AC, Hutton P, Chiche JD, et al. Association between trends in clinical variables and outcome in intensive care patients with faecal peritonitis: analysis of the GenOSept cohort. Crit Care. 2015 [citado 28/12/2019]; 19 (1):210. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432819/

  6. Gaye I, Alassane Leye P, Mour Traoré M, Ibrahima Ndiaye P, Boubacar H, Diawo Bah M, et al. Perioperative management of emergency abdominal surgery in adult patients at the Aristide Le Dantec University Hospital. Pan Afr Med J. 2016 [citado 28/12/2019];24:190. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072862/

  7. Roque L, Roque M, Gómez N, Salinas M, Moyano I, Pérez J. Factores pronósticos de mortalidad en pacientes con peritonitis secundaria hospitalizados en la unidad cuidados intensivos. Rev Cubana Med Intens Emerg. 2016 [citado 28/12/2019]; 15 (2): 16-33. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/138/pdf_

  8. Pereira Rochan N, Costa Fortes R. Total lymphocyte count and serum albumin as predictors of nutritional risk in surgical patients. Arq Bras Cir Dig. 2015 [citado 28/12/2019];28(3):193-96. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737361/

  9. Arun Kumar RV, Channabasappa SM. A retrospective cohort study of perioperative prognostic factors associated with intra-abdominal sepsis. Anesth Essays Res. 2016 [citado 28/12/2019];10(1):50-3. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767092/

  10. Vincent JL, Ferreira F, Moreno R. Scoring systems for assessing organ dysfunction and survival. Crit Care Clin. 2000; 16(2):353-66.

  11. Wittmann DH. Intraabdominal infection. World J Surg. 1990; 14:145-7.

  12. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985; 13(10):818-29.

  13. 13.Wacha H, Linder MM, Feldmann U, Wesch G, Gundlach E, Steifensand RA. Mannheim peritonitis index–prediction of risk of death from peritonitis construction of a statistical and validation of an empirically based index. Theor Surg. 1987; 1:169-77.

  14. Ayandipo OO, Afuwape OO, Irabor DO, Abdurrazzaaq AI, Nwafulum NA. Outcome oflaparotomy for peritonitis in 302 consecutive patients in Ibadan, Nigeria. Ann Ibd Pg Med. 2016 [citado 28/12/2019];4(1):30-4. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049599/pdf/AIPM-14-30.pdf

  15. 15.Majtan P, Neumann J, Kocián P, Hoch J. Perspective of patients undergoing surgery for secondary peritonitis. Rozhl Chir. 2015 [citado 28/12/2019];94(5):199-203. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26112685/

  16. Ghosh PS, Mukherjee R, Sarkar S, Halder SK, Dhar D. Epidemiology of Secondary Peritonitis: Analysis of 545 cases. Int J Sci Stud. 2016 [citado 28/12/2019];3(12). Disponible en: https://www.semanticscholar.org/paper/Epidemiology-of-Secondary-Peritonitis%3A-Analysis-of-Ghosh-Mukherjee/1acbfd16b6798fa329cadd8087a38a90c60ff141

  17. Sonoda A, Ohnishi S, Nakao S, Iwashita Y, Hashimoto N, Ishida K, et al. Factors afecting serum albumin in the perioperative period of colorectal surgery: a retrospective study. BMC Res Notes. 2015 [citado 28/12/2019]; 8: 638-45. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26530188/

  18. Nazaretyan VV, Lukach VN, Kulikov AV. Predictors of un favorable outcome in patients with abdominal sepsis. Anesteziol Reanimatol. 2017; 61:209-15.

  19. Kim S, McClave SA, Martindale RG, Miller KR, Hurt RT. Hypoalbuminemia and Clinical Outcomes: What is the Mechanism behind the Relationship?Am Surg. 2017;83(11):1220-27.

  20. 20.Labgaa I, Joliat GR, Kefleyesus A, Mantziari S, Schäfer M, Demartines M, et al. Is postoperative decrease of serum albumin an early predictor of complications after major abdominal surgery? A prospective cohort study in a European centre. BMJ Open. 2017 [citado 28/12/2019];7(4). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775466/




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

MediSan. 2020;24