Gómez GMG, Monares ZE, Franco-Granillo J, Aguirre-Sánchez JS, Chaires GR, Escala BMV

Language: Spanish
References: 10
Page: 18-22
PDF size: 219.28 Kb.

ABSTRACT

Introduction: The 2019 coronavirus disease (COVID-19) pandemic continues to challenge health care systems around the world. In the past two months, only a few studies have looked at prognostic factors for death in COVID-19 patients. It is therefore of great clinical relevance that there are analysis of prognostic scales, which help to prevail over the severity of patients, for decision-making and timely actions that avoid complications and increase in hospital supplies. In the present study, the use of the simplified SOFA scale is proposed, which is a prognostic scale that consists of clinical evaluation, without any requirements for office studies. Objectives: To demonstrate the diagnostic certainty through the concordance and degree of agreement of using SOFA-simplified and SOFA. Material and methods: Retrospective cohort study in COVID-19 patients admitted to ICU. Demographic data, laboratory results and immunological indicators were collected, in order to analyze and compare prognostic scales. Qualitative variables are reported as frequencies and proportions. Quantitative variables such as median with interquartile range or mean with standard deviation. The sample size is calculated with Epi Info version 5.4.6 and OpenEpi. Both prognostic scales are compared; as well as, survival of Kaplan Meier. The superposition of both scales is analyzed to demonstrate the diagnostic certainty by means of ROC curves, the area under the curve is assessed and for the comparison between them an agreement with intraclass correlation coefficient (ICC) and representation by Bland Altman will be made. The program to use for data analysis IBM SPSS Statistics 24, application Epi Info version 5.4.6 and OpenEpi. Results: The degree of agreement measured by intraclass correlation index was 0.688 (95% CI 0.405-0.836) with significant p (p < 0.001), which translates into a high degree of agreement between SOFA and simplified SOFA and a similar performance. Conclusion: According to the high degree of agreement presented in this study, the simplified SOFA scale could be used as a substitute to predict severity in patients with COVID in health areas where laboratory equipment is not available, identifying the severity in a timely manner, improve timely care and reduce mortality.

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