de Souza ABII, Cavalcanti AR, P Imparato JC, Rezende KM

Language: Spanish
References: 0
Page: 146-153
PDF size: 0. Kb.

ABSTRACT

Mesenchymal stem cells (MSCs) are adult stem cells that have the ability to differentiate into various cell types. A rich source of mesenchymal stem cells can be obtained from dental tissues such as the apical papilla. The objective of this work was to extract stem cells from the apical papilla of third human molars to see its feasibility to be used in clinical practice. Testing of cell separation with Stro-1 and study of kinetics were performed. As a result, these cells had a high rate of pro- liferation, formation of colonies and easy access. We conclude that the use of stem cells obtained from teeth can be a good alternative because they are easy to access, high cell viability and positive expression for mesenchymal cell markers. Tissue regeneration or new formation of craniofacial structures is the future of regenerative medicine, offering a possibility for treatment of congenital malformations, traumas and other diseases.