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2020, Number 4

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Rev Mex Patol Clin Med Lab 2020; 67 (4)

The role of the clinical pathologist in COVID-19. A Peruvian perspective

La RFB, Urquizo B

Language: Spanish
References: 25
Page: 185-189
PDF size: 203.90 Kb.


ABSTRACT

The SARS-CoV-2 virus, the etiological agent of COVID-19, was discovered recently, in the midst of a pandemic that has resulted in great morbidity and mortality worldwide, at great economic and social cost. Clinical pathology as a specialty gives the physician the ability to help reach a diagnosis through laboratory tests, monitor and control the evolution of diseases, evaluate the prognosis of patients, manage the clinical laboratory, develop research and teaching activities in order to gain a better understanding of diseases and their consequences in the human body. In the context of the COVID-19 pandemic, the clinical pathologist plays an important role in these areas. Although the most obvious laboratory diagnostic aid has been the detection of the SARS-CoV-2 virus through molecular tests, the scope of laboratory medicine goes further, constituting a fundamental tool in the management and control of the disease.


REFERENCES

  1. Coronavirus disease 2019 (COVID-19): situation report-51. Geneva: World Health Organization; Available in: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200311-sitrep-51-covid-19.pdf.

  2. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395 (10223): 497-506. doi: 10.1016/S0140-6736(20)30183-5.

  3. Ministerio de Salud. Atención y manejo clínico de casos de COVID19. Escenario de transmisión focalizada. Lima-Perú; 2020.

  4. Bedford J, Enria D, Giesecke J, Heymann DL, Ihekweazu C, Kobinger G et al. COVID-19: towards controlling of a pandemic. Lancet. 2020; 395 (10229): 1015-118. doi: 10.1016/S0140-6736(20)30673-5.

  5. Pan F, Ye T, Sun P, Gui S, Liang B, Li L et al. Time course of lung changes at chest CT during recovery from coronavirus disease 2019 (COVID-19). Radiology. 2020; 295 (3): 715-721.

  6. Pamo-Reyna OG. El residentado médico en el Perú. Diagnóstico. 2019; 58 (3): 117-121.

  7. Lippi G, Simundic AM, Plebani M. Potential preanalytical and analytical vulnerabilities in the laboratory diagnosis of coronavirus disease 2019 (COVID-19). Clin Chem Lab Med. 2020; 58 (7): 1070-1076.

  8. Woloshin S, Patel N, Kesselheim AS. False negative tests for SARS-CoV-2 infection - challenges and implications. N Engl J Med. 2020; 383 (6): e38.

  9. Carter LJ, Garner LV, Smoot JW, Li Y, Zhou Q, Saveson CJ et al. Assay techniques and test development for COVID-19 diagnosis. ACS Cent Sci. 2020; 6 (5): 591-605. doi: 10.1021/acscentsci.0c00501.

  10. Li C, Zhao C, Bao J, Tang B, Wang Y, Gu B. Laboratory diagnosis of coronavirus disease-2019 (COVID-19). Clin Chim Acta. 2020; 510: 35-46. doi: 10.1016/j.cca.2020.06.045.

  11. Bastian I, Waring L. The Royal College of Pathologists of Australasia (RCPA) position statement on COVID-19. Aust J Gen Pract. 2020; 49. doi: 10.31128/AJGP-COVID-09.

  12. Petherick A. Developing antibody tests for SARS-CoV-2. Lancet. 2020; 395 (10230): 1101-1102. doi: 10.1016/S0140-6736(20)30788-1.

  13. Amanat F, Stadlbauer D, Strohmeier S, Nguyen THO, Chromikova V, McMahon M et al. A serological assay to detect SARS-CoV-2 seroconversion in humans. Nat Med. 2020; 26 (7): 1033-1036. doi: 10.1038/s41591-020-0913-5.

  14. Theel ES, Slev P, Wheeler S, Couturier MR, Wong SJ, Kadkhoda K. The role of antibody testing for SARS-CoV-2: is there one? J Clin Microbiol. 2020; 58 (8): e00797-20.

  15. Lippi G, Plebani M. SARS-CoV-2 antibodies titration: a reappraisal. Ann Transl Med. 2020; 8 (16): 1032. doi: 10.21037/atm-20-5361.

  16. Lisboa Bastos M, Tavaziva G, Abidi SK, Campbell JR, Haraoui LP, Johnston JC et al. Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis. BMJ. 2020; 370:m2516. doi: 10.1136/bmj.m2516.

  17. Herroelen PH, Martens GA, De Smet D, Swaerts K, Decavele AS. Humoral immune response to SARS-CoV-2. Am J Clin Pathol. 2020; 154 (5): 610-619. doi: 10.1093/ajcp/aqaa140.

  18. Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020; 46 (5): 846-848.

  19. Coomes EA, Haghbayan H. Interleukin-6 in Covid-19: A systematic review and meta-analysis. Rev Med Virol. 2020; 30 (6): 1-9.

  20. Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020; 18 (4): 844-847.

  21. Gehrie E, Tormey CA, Sanford KW. Transfusion Service Response to the COVID-19 Pandemic. Am J Clin Pathol. 2020; 154 (3): 280-285. doi: 10.1093/ajcp/aqaa111.

  22. Altuntas F, Ata N, Yigenoglu TN, Basci S, Dal MS, Korkmaz S et al. Convalescent plasma therapy in patients with COVID-19. Transfus Apher Sci. 2020: 102955. doi: 10.1016/j.transci.2020.102955.

  23. Roback JD, Guarner J. Convalescent plasma to treat COVID-19: possibilities and challenges. JAMA. 2020; 323 (16): 1561-1562.

  24. Kroft SH. The evolution of the clinical pathologist. Am J Clin Pathol. 2018; 150 (4): 283-284. doi: 10.1093/ajcp/aqy119.

  25. Sánchez-Duque JA. Medical education in pandemic time: The case of coronavirus disease 2019 (COVID-19). Educación Médica. 2020; 21 (4): 259-26. doi: 10.1016/j.edumed.2020.05.005.




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