Córdova-Serrano R, Cevallos-Espinel J, Vargas-Maradiaga AL, Lome-Maldonado C, Candelaria-Hernández M

Language: Spanish
References: 14
Page: 50-55
PDF size: 275.21 Kb.

ABSTRACT

Background: Marginal zone lymphoma is classified in nodal, splenic and MALT (mucose associated lymphoid tissue). Regarding MALT, the lung presentation as primary site constitutes less than 1% of all lymphomas.
Clinical case: A 66-year-old male patient with respiratory symptoms of 2 months of evolution, in whom a computed tomography showed consolidation in the left upper pulmonary lobe. Lymphoma of lymphoid tissue associated with the pulmonary bronchus was histologically documented. Positron emission computed tomography with flurodeoxyglucose ruled out extrapulmonary metabolic activity. He received treatment with 4 cycles of RCVP. There is no clinical evidence of progression after one year of surveillance.
Conclusions: Bronchus-associated MALT (BALT) constitutes less than 1% of lymphomas. National epidemiological studies are required.

REFERENCES

1. Cock JR, Isaacson PG, Chott A, et al. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). Lyon. International Agency for Research on Cancer 2017; 259-262.

2. Borie R, Wislez M, Thabut G, Antoine M, et al. Clinical characteristics and prognostic factors of pulmonary MALT lymphoma. Eur Respir J 2009; 34: 1408-1416 doi. 10.1183/09031936.00039309.

3. Arkenau HT, Gordon C, Cunningham D, Norman A, et al. Mucosa associated lymphoid tissue lymphoma of the lung: the Royal Marsden Hospital experience. Leuk Lymphoma 2007; 48: 547-550. doi. 10.1080/10428190601094388.

4. Zinzani PL, Magagnoli M, Galieni P, Martelli M, et al. Nongastrointestinal low-grade mucosa-associated lymphoid tissue lymphoma: analysis of 75 patients. J Clin Oncol 1999; 17: 1254. doi. 10.1200/JCO.1999.17.4.1254.

5. Nakamura N, Yamada G, Itoh T y col. Pulmonary MALT lymphoma with amyloid production in a patient with primary Sjogren’s syndrome. Intern Med 2002; 41 (4): 309-311. doi. 10.2169/internalmedicine.41.309.

6. Arnaoutakis K. Bronchus-associated lymphoid tissue lymphomas. South Med J 2009; 102: 1229-1233. doi. 10.1097/ SMJ.0b013e3181bfdd2d.

7. Ahmed S, Kussick SJ, Siddiqui AK, Bhuiya TA, et al. Bronchialassociated lymphoid tissue lymphoma: a clinical study of a rare disease. Eur J Cancer 2004; 40: 1320-6. doi. 10.1016/j. ejca.2004.02.006.

8. Bermas K, Cooper D, Boffa D. BALToma (bronchus-associated lymphoid tissue lymphoma) presenting as enlarging ground glass opacities. Chest 2009; 136 (4): 33S. https:// doi.org/10.1378/chest.136.4_MeetingAbstracts.33S-c.

9. Girinsky T, Paumier A, Ferme C, Hanna C, et al. Lowdose radiation treatment in pulmonary mucosa-associated lymphoid tissue lymphoma: a plausible approach? A single-institution experience in 10 patients. Int J Radiat Oncol Biol Phys 2012; 83(3): e385-e389. doi. 10.1016/j. ijrobp.2012.01.005.

10. Inadome Y, Ikezawa T, Oyasu R, Noguchi M. Malignant lymphoma of bronchus-associated lymphoid tissue coexistent with pulmonary tuberculosis. Pathol Int 2001; 51: 807-811. doi. 10.1046/j.1440-1827.2001.01272.x.

11. Lee H, Yang B, Nam B, Jeong BH, et al. Treatment outcomes in patients with extranodal marginal zone B-cell lymphoma of the lung. J Thorac Cardiovasc Surg 2017; 154 (1): 342- 349. doi. 10.1016/j.jtcvs.2017.03.043.

12. Zhao S, Zhang Li, Zhenyang Gu, Zhu C, et al. Clinical manifestations of pulmonary mucosa – associated lymphoid tissue lymphoma: single-center experience with 18 patients. Onco Targets Ther 2018; 11: 555-561. doi. 10.2147/ OTT.S147275.

13. Laszlo D, Steffanoni S, Andreola G, Balzano R, et al. Bronchial-associated lymphoid tissue (BALT) lymphoma: A multicenter retrospective analysis. Blood 2004; 104: 4583. https://doi.org /10.1182/blood. V104.11.4583.4583.

14. Bilici A, Seker M, Ustaalioglu B, Canpolat N, et al. Pulmonary BALT lymphoma successfully treated with eight cycles weekly rituximab: Report of first case and F-18 FDG PET/CT images. J Korean Med Sci 2011; 26: 574-6. doi. 10.3346/ jkms.2011.26.4.574.