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2021, Number 1

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Sal Jal 2021; 8 (1)

Seroprevalencia de Virus Herpes Simple Tipo 1 en una muestra poblacional de la Zona Metropolitana de Guadalajara y municipios aledaños

Gamboa-Cañedo EA, Martínez-Limón FJ, Santibañez-Escobar PL, Padilla-Rosas M, Nava-Villalba M
Full text How to cite this article

Language: Spanish
References: 25
Page: 26-34
PDF size: 292.63 Kb.


Key words:

virus diseases, ELISA, antibodies, seroepidemiology.

ABSTRACT

Introduction: Due to the diversity of clinical presentations that Herpes Simplex Virus type 1 (HSV-1) infection may developing, accurate recording of its incidence, is complicated; outstanding the fact that in a signifi cant number of cases the primary infection is subclinical, another underdiagnosed or undervalued. One approach to determine the degree of population exposure is via seroprevalence, knowing this indicator, the specialists and those responsible for health policies can be guided to consider prevention, diagnosis and treatment measures. Objective: To determine the HSV-1 seroprevalence in a population sample from the Guadalajara Metropolitan Area (GMA) and to assess whether positive cases show a correlation with sociodemographic characteristics. Methods: Descriptive cross-sectional study, which 75µL of remnant serum was collect from patients aged 0-80 years, who attended the Clinical Pathology Laboratory of the Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Subsequently, ELISA assays to detect HSV-1 (IgG), were performed. Results: From 133 samples collected, 69% were women with 72% positive cases in them and 59% in men group. Seropositivity rises as age increased (Spearman, *p = .0244). On average, 95% of the subjects older than 30 years present antibodies against HSV-1. Th e minimum period registered (0-2 years old) presented 11% seroprevalence. Regarding occupation, most of subjects evaluated are housewives (54.02%) with 91.5% of seropositivity. Although it is not signifi cant, a negative trend between the lowest degree of studies achieved and a high seropositivity was observed. Conclusions: HSV-1 seroprevalence was high in this GMA population sample (67.66%). Th e research revealed a trend of infection among vulnerable groups and it confi rmed that seropositivity increases in adults.


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Sal Jal. 2021;8