medigraphic.com
ISSN 1029-3019 (Electronic)

2020, Number 05

<< Back Next >>

MediSan 2020; 24 (05)

Clinical and epidemiological characteristics of patients with asymptomatic clinical course of COVID-19 in Santiago de Cuba province

Valdés GLE, León BD, Neira PA, Jaqueman DY

Language: Spanish
References: 20
Page: 810-822
PDF size: 1084.42 Kb.


ABSTRACT

Introduction: The COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which is presented in an asymptomatic way in up to 80 % of the cases at world level.
Objective: To characterize the patients with asymptomatic clinical course of the COVID-19.
Methods: An observational, descriptive and cross-sectional study was carried out in Santiago de Cuba province, with retrospective gathering of the information, from March to May, 2020, belonging to 13 patients with diagnosis of the disease and no symptomatic manifestation of it.
Results: Of the patients with positive results for coronavirus in the province, 26,0 % were asymptomatic; there was a predominance of the 20-39 years-old (38,4 %), and the 60 and more years (30,7 %) in these age groups, as well as of the female sex (84,6 %). Equally, 30,7 % suffered from non-communicable chronic diseases and 38,5 % turned out to be infection source to other people.
Conclusions: The frequency of asymptomatic patients in Santiago de Cuba was different from that notified in the rest of the country and in other nations, which could be conditioned by the absence of episodes or outbreaks and the low registered incidence; nevertheless, in the analysis of the variables there were no discrepancies with the reports on patients with this clinical form of the disease.


REFERENCES

  1. Organización Mundial de la Salud. COVID-19. Hoja Informativa. 2020 Abr [citado 20/05/2020]. Disponible en: https://files.sld.cu/cpicm-cmw/files/2020/04/Hoja-inf-abril.pdf.

  2. Lo que se sabe de los asintomáticos con COVID-19. Revista La Vanguardia. 2020 Abr [citado 20/05/2020]. Disponible en: https://www.vanguardia.com/colombia/explicador-lo-que-se-sabe-de-los-asintomaticos-con-el-covid-19-JA2288957.

  3. Cuba. Ministerio de Salud Pública de la República de Cuba, Centro para el Control Estatal de Medicamentos, Equipos y Dispositivos Médicos. Coronavirus en Cuba. Información Oficial del MINSAP, 12 de agosto de 2020. La Habana: CECMED; 2020 [citado 20/05/2020]. Disponible en: https://www.cecmed.cu/noticias/coronavirus-cuba-12-agosto-2020.

  4. Ministerio de Salud Pública de la República de Cuba, Centro para el Control Estatal de Medicamentos, Equipos y Dispositivos Médicos. Coronavirus en Cuba. Información Oficial del MINSAP, 22 de mayo de 2020. La Habana: CECMED; 2020 [citado 20/05/2020]. Disponible en: https://www.cecmed.cu/noticias/coronavirus-cuba-22-mayo-2020.

  5. Medsalud. ¿Cómo evoluciona la infección por el VIH? [citado 20/05/2020]. Disponible en: https://www.msdsalud.es/cuidar-en/vih-sida/vih-sida-aprende/evoluciona-infeccion-vih.html.

  6. Sitio Oficial de Gobierno del Ministerio de Salud Pública en Cuba. COVID-19. Parte de cierre del 22 de abril 2020 a las 12 de la noche [citado 20/05/2020]. Disponible en: https://salud.msp.gob.cu/2020/04/23/.

  7. Heneghan C, Brassey J, Jefferson T. COVID 19: What proportion are asymptomatic? Centre for Evidence-Based Medicine. CEBM. 2020 Abr [citado 20/05/2020]. Disponible en: https://www.cebm.net/covid-19/covid-19-what-proportion-are-asymptomatic/.

  8. Oxford COVID-19 Evidence Service. Transmission Dynamic Centre for Evidence-Based Medicine. CEBM. 2020 Abr [citado 20/05/2020]. Disponible en: https://www.cebm.net/oxford-covid-19-evidence-service/.

  9. Antoni T. Los casos asintomáticos. LaVanguardia.com 23 de abril de 2020 [citado 20/05/2020]. Disponible en: https://www.lavanguardia.com/vida/20200423/48683512885/los-casos-asintomaticos.html.

  10. Fuminari M, Ryota M, Hiroshi N. Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks with Laboratory Testing in Japan. J Epidemiol. 2018 [citado 20/05/2020];28(9):382-7. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111106/.

  11. Kenji M, Tetsuro K, Chowell G. Transmission potential of modified measles during an outbreak, Japan, March? May 2018. Euro Surveill. 2018 [citado 20/05/2020];23(24). Disponible en: https://doi.org/10.2807/1560-7917.EN.2018.23.24.1800239.

  12. Zhiliang H, Ci S, Chuanjun X, Guangfu J, Yaling C, Xin X, et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Sci China Life Sci. 2020 [citado 20/05/2020];63(5):706-11. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088568/pdf/11427_2020_Article_1661.pdf.

  13. Coiras M, Serrano S; Grupo de Análisis Científico de Coronavirus del Instituto de Salud Carlos III. Informe del Grupo de Análisis Científico de Coronavirus del ISCIII (GACC-ISCIII). Madrid: Ministerio de Ciencia e Innovación; 2020 [citado 20/05/2020]. Disponible en: https://www.conprueba.es/sites/default/files/noticias/2020-05/MANIFESTACIONES%20CL%C3%8DNICAS%20DE%20LA%20ENFERMEDAD%20COVID-19.pdf.

  14. Oran DP, Topol EJ. Prevalence of asymptomatic SARS-CoV-2 infection: A narrative Review. Ann Intern Med. 2020 Jun [citado 20/05/2020]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281624/pdf/aim-olf-M203012.pdf.

  15. Sijia T, Nan H, Jing L, Kun C, Xuqin K, Zhenjun X, et al. Characteristics of COVID-19 infection in. Beijing. J Infect. 2020 [citado 20/05/2020];80(4):401-6. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102527/.

  16. González Moraga FJ. Por qué Covid-19 en algunas personas es asintomático, mientras que en otras es letal. Infosalus.com [actualizado 02/05/2020; citado 23/05/2020]. Disponible en: https://www.infosalus.com/salud-investigacion/noticia-covid-19-algunas-personas-asintomatico-mientras-otras-letal-20200423083543.html.

  17. La experiencia de España frente al coronavirus, lecciones para otros países. Noticias ONU. 8 Abr 2020 [citado 20/05/2020]. Disponible en https://news.un.org/es/story/2020/04/1472622.

  18. Mizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill. 2020 [citado 20/05/2020];25(10). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078829/pdf/eurosurv-25-10-1.pdf.

  19. World Health Organization. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). 16-24 February 2020. Geneva: WHO; 2020 [citado 20/05/2020]. Disponible en: https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf.

  20. Aragón-Nogales R, Vargas-Almanza I, Miranda-Novales MG. COVID-19 por SARS-CoV-2: la nueva emergencia mundial. Rev Mex Pediatr 2019 [citado 20/05/2020];86(6);213-8. Disponible en: https://www.medigraphic.com/pdfs/pediat/sp-2019/sp196a.pdf.




2020     |     www.medigraphic.com