Chávez IMI, Hernández DPA, Querol BN, González VD

Language: Spanish
References: 15
Page: 875-885
PDF size: 976.47 Kb.

ABSTRACT

Introduction: The idiopathic hypercalciuria is a frequent and not very recognized metabolic disorder which clinical course depends in great extent on changes in the dietary habits from the childhood.
Objective: To characterize children and adolescents with idiopathic hypercalciuria according to the clinical, epidemiological and therapeutic variables.
Methods: An observational, longitudinal and prospective investigation was carried out in 44 patients with idiopathic hypercalciuria, assisted in the Miscellaneous Service of Antonio María Béguez Cesar Southern Teaching Children Hospital in Santiago de Cuba, from January, 2014 to December, 2015.
Results: The symptomatic forms of the disease were the most frequent (68.2 %); also, the male sex prevailed (72.7 %) and the average age was 7.2 ± 4 years. Statistical association existed among the preschool and school ages as for the diagnosis of idiopathic hypercalciuria. The recurrent macroscopic hematuria was the most usual symptom in the majority of cases (59.1 %); as long as, the 25.0 % of patients presented renal lithiasis and the diet and liquids-based non pharmacological treatment was associated with a satisfactory evolution in 68.2 % of the affected patients, although the remaining 31.8 % needed drugs treatment.
Conclusions: The clinical and epidemiological characteristics of patients with idiopathic hypercalciuria of this case material didn't differ from the ones registered worldwide, taking into account that this metabolic disorder is relatively frequent in pediatric services.

REFERENCES

1. García Nieto VM, Luis Yanes MI, Tejera Carreño P, Pérez Suarez G, Moraleda Mesa T. La hipercalciuria idiopática revisada. ¿Anomalía metabólica o enfermedad? Nefrología. 2019;39(6):592-602.

2. Elder JS. Urinary lithiasis. En: Kliegman RM, Stanton BF, St. Geme J, Schor NF. Nelson Texbook of Pediatrics. 20 ed. Philadelphia: Elsevier; 2015. p. 2600-4.

3. Ulloa Barón C. Factores asociados al desarrollo de formas sintomáticas de hipercalciuria idiopática en niños de la Fundación Cardioinfantil. Cienc Salud Bogotá. 2008;6(1):26-35.

4. González-Lamuño Leguina D. Hipercalciuria. Pediatr Integral. 2017;21(8):529-40.

5. Orta N, Sanna V, Moriyón JC, de Orta S, Domínguez L, Zibaoui, et al. Hematuria en niños: análisis de la casuística en un centro de referencia nacional. Valencia, Venezuela. Rev Chil Pediatr. 2001 [citado 02/06/2020];72(2):92-9. Disponible en: http://plataforma.revistachilenadepediatria.cl/index.php/rchped/article/view/1730

6. Liern M, Bohorquez M, Vallejo G. Treatment of idiopathic hypercalciuria and its impact on associated diseases. Arch Argent Pediatr. 2013;111(2):110-4.

7. Ajdadi E, Esteghamati M, Ghasemi K, Zakeri Shahvari S. Comparison of urinary sodium and potassium in children older than two with idiopathic hypercalciuria and a healthy control group in Bandar-Abbas, Iran, in 2013. Electron Physician. 2014;6(3):872-6.

8. Ordóñez Álvarez FA. Hematuria: actitud diagnóstica. Pediatr Integral. 2017;21(8):518-28.

9. Antón Gamero M. Hematuria y proteinuria. En: Asociación Española de Pediatría de Atención Primaria. Curso Actualización en Pediatría 2018. Madrid: Lúa Ediciones; 2018. p. 53-9.

10. Campo Sánchez L, Durán Álvarez S, Hernández Hernández JS, Sosa Palacio O. Etiología de la hematuria monosintomática en pediatría. Revista Cubana de Pediatría. 2019;91(2):809.

11. Quiñones-Vázquez S, Liriano-Ricabal MR, Santana-Porbén S, Salabarría-González JR. Índice calcio-creatinina en una muestra matutina de orina para la estimación de hipercalciuria asociada con hematuria no glomerular observada en edades infanto-juveniles. Bol Med Hosp Infant Mex. 2018;75:41-8.

12. Akhavansepahi M, Hoseini BL, Tabarai Y. Screening of hypercalciuria among children with persistent asymptomatic hematuria. J Biostat Epidemiol. 2017;3(3-4):106-10.

13. Mulic B, Mulic M, Muminovic S, Mulic M, Vujosevic S, Peco-Antic A. Calciuria in children with primary mono-symptomatic nocturnal enuresis. Sanamed. 2018;13(3):281-86.

14. Adrian Copajira M, Durán Álvarez S, Irisarry Rojo G, Hernández-Hernández JS, Sosa Palacios O. Hipercalciuria idiopática como factor predisponente de infección urinaria. Revista Cubana de Pediatría. 2019; 91(3):812.

15. Rodrigo Jiménez MD, Vicente Calderón C. Litiasis renal e hipercalciuria idiopática. Protoc Diagn Ter Pediatr. 2014;1:155-70.