Cirugía y Cirujanos

Contents by Year, Volume and Issue

Table of Contents

General Information

Instructions for Authors

Message to Editor

Editorial Board

>Journals >Cirugía y Cirujanos >Year 2009, Issue 2

Lima-Gómez V, Ojeda-Cruz P
Concordance of two retinal mapping techniques to detect diabetic macular edema
Cir Cir 2009; 77 (2)

Language: Español
References: 20
Page: 89-93
PDF: 89.73 Kb.

Full text


Background: Optical coherence tomography quantifies retinal thickness, localizes diabetic macular edema, and determines whether it implies visual risk. Evaluation is standardized by the macular mapping technique in two versions: 6 mm and 3.45 mm. The latter version measures with greater detail the zone adjacent to the central 1000 µm but does not evaluate the entire macula. Concordance between maps was evaluated in order to define which version better evaluated diabetic macular edema prospectively.
Methods: The rate and 95% confidence intervals (95% CI) of eyes with diabetic macular edema, which had thickening adjacent to the central 1000 µm, was identified in fields of the 6-mm map and in the corresponding fields of the 3.45-mm map. The disparity between rates was identified using McNemar test, and concordance between fields was determined using kappa coefficient.
Results: The rate of thickening in the studied area ranged from 31.9 to 50% with overlapping 95% CI between corresponding fields. Although significant differences existed (p ‹0.05), there was good concordance for 3/8 comparisons and very good concordance in five.
Conclusions: Information generated by the 6-mm macular mapping was as valid as that generated by the 3.45 mapping to identify thickening adjacent to the central 1000 µm. We recommend using the 6-mm mapping prior to surgery because it has the advantage of completely measuring the macula.

Key words: Diabetic macular edema, diabetic retinopathy, macular mapping, optical coherence tomography.


  1. Ryan SJ. Retina. St. Louis: Mosby-Yearbook; 2002. p. 1299.

  2. Ciulla TA, Amador AG, Zinman B. Diabetic retinopathy and diabetic macular edema. Diabetes Care 2003;26:2653-2664.

  3. Brown JC, Solomon SD, Bressler SB, Schachat AP, DiBernardo C, Bressler NM. Detection of diabetic foveal edema. Contact lens biomicroscopy compared with optical coherence tomography. Arch Ophthalmol 2004;122:330-335.

  4. Browning DJ, McOwen MDD, Bowen RM, O’Marah TL. Comparison of the clinical diagnosis of diabetic macular edema with diagnosis by optical coherence tomography. Ophthalmology 2004;111:712-715.

  5. American Academy of Ophthalmology. Retina panel. Diabetic retinopathy. Preferred practice patterns. San Francisco: American Academy of Ophthalmology; 2003. pp. 113-114.

  6. Polito A, Del Borrello M, Isola M, Zemella N, Bandello F. Repeatability and reproducibility of fast macular thickness mapping with Stratus optical coherence tomography. Arch Ophthalmol 2005;123:1330-1337.

  7. Chan A, Duker JS, Ko TH, Fujimoto JG, Schuman JS. Normal macular thickness in healthy eyes using Stratus optical coherence tomography. Arch Ophthalmol 2006;124:193-198.

  8. Massin P, Erginay A, Haouchine B, Mehidi AB, Paques M, Gaudric A. Retinal thickness in healthy and diabetic subjects measured using optical coherence tomography mapping software. Eur J Ophthalmol 2002;12:102-108.

  9. Goebel W, Kretzchar-Gross T. Retinal thickness in diabetic retinopathy. Retina 2002;22:759-767.

  10. Lima GV. Comparación del grosor macular con y sin edema en pacientes diabéticos mexicanos. Rev Mex Oftalmol 2007;81:214-218.

  11. Frank RN, Schulz L, Abe K, Iezzi R. Temporal variation in diabetic macular edema measured by optical coherence tomography. Ophthalmology 2004; 111:211-217.

  12. Degenring RF, Aschmoneitt I, Kamppeter B, Budde W, Jonas JB. Optical coherence tomography and confocal scanning laser tomography for the assessment of macular edema. Am J Ophthalmol 2004;138:354-361.

  13. Polito A, Del Borrello M, Polin G, Burlan F, Isola M, Bandello F. Diurnal variation of clinically significant diabetic macular edema measured by the Stratus OCT. Retina 2006;26:14-20.

  14. Álvarez CM, Fromow GH, Guerrero NJ, Quiroz MH. Correlación entre el grosor macular y capacidad visual en pacientes con retinopatía diabética y edema macular clínicamente significativo. Rev Mex Oftalmol 2004;78:230-236.

  15. Sadda SR, Wu Z, Walsh AC, Richine L, Dougall J, Cortez R, et al. Errors in retinal thickness measurements obtained by optical coherence tomography. Ophthalmology 2006;113:285-293.

  16. Catier A, Tadayoni R, Paques M, Erginay A, Hoouchine B, Gaudric A, et al. Characterization of macular edema from various etiologies by optical coherence tomography. Am J Ophthalmol 2005;14:200-206.

  17. Diabetic Retinopathy Clinical Research Network, Krzystolik MG, Strauber SF, Aiello LP, Beck RW, Berger BB, Bressler NM, et al. Reproducibility of macular thickness and volume using Zeiss optical coherence tomography in patients with diabetic macular edema. Ophthalmology 2007;114:1520-1525.

  18. Vujosevic SE, Midena E, Pilotto E, Raddin PP, Chiesa L, Cavarzeran F. Diabetic macular edema: correlation between microperimetry and optical coherence tomography findings. Invest Ophthalmol Vis Sci 2006;47:3044-3051.

  19. Campbell RJ, Coupland SG, Buhrmann RR, Kertes PJ. Optimal optical coherence tomography-based measures in the diagnosis of clinically significant macular edema: retinal volume vs. foveal thickness. Arch Ophthalmol 2007;125:619-623.

  20. Gass JD. Stereoscopic Atlas of Macular Diseases. St Louis: Mosby-Yearbook; 1997. p. 2.

>Journals >Cirugía y Cirujanos >Year 2009, Issue 2

· Journal Index 
· Links 

Copyright 2019