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>Journals >Cirugía y Cirujanos >Year 2013, Issue 2


Menéndez-Sánchez P, Villarejo-Campos P, Padilla-Valverde D, Menéndez-Rubio JM, Rodríguez-Montes JA
Marcadores tumorales en el cáncer colorrectal
Cir Cir 2013; 81 (2)

Language: Español
References: 38
Page: 169-175
PDF: 1016.38 Kb.


Full text




ABSTRACT

Introduction: In 2008, colorectal cancer represented the third most commonly diagnosed tumor in Spain, and the second tumor with more deaths. Despite the new potential biomarkers in colorectal cancer, there are many challenges that need to be overcome, being necessary the standardization of its determinations.
Discussion: The continuous advance in tumor disease knowledge makes this review a summary of the current accepted, recommended and studied tumor markers for the diagnosis and monitoring of colorectal cancer, such as fecal markers, tissue markers and serological markers, and various prognostic markers on which there are different lines of treatment in colorectal cancer.
Conclusions: Oncological guidelines recommend only a minority of tumor markers for routine use, such as the study of fecal occult blood, CEA determination in the postoperative followup, microsatellites instability to identify people susceptible to hereditary nonpolyposis colorectal cáncer, and mutation of APC in the diagnosis of familial adenomatous polyposis.


Key words: tumoral markers, colorectal cancer.


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