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>Journals >Cirugía y Cirujanos >Year 2004, Issue 5

Sotelo-Cruz N, Cordero-Olivares A, Ramírez-Rodríguez C, López-Cervantes G, Hurtado-Valenzuela J, López-Cervantes BM
Persistent hyperinsulinemic hypoglycemia. Two cases report
Cir Cir 2004; 72 (5)

Language: Español
References: 17
Page: 409-414
PDF: 123.56 Kb.

Full text


We report two cases of infants who presented seizures and persistent hypoglycemia. In both infants, we established diagnosis of persistent hypoglycemia by hyperinsulinism (PHH); glycemic/insulinic ratio was > 0.3, and we found no pancreatic changes by means of other diagnostic procedures. The medical treatment consisted of hydrocortisone, diazoxide, and octreotide without response. Definitive treatment made was sub-total pancreatectomy; postoperatory evolution was satisfactory, and the histologic report showed changes in Langerhans islet of nesidioblastosis. We conclude that PHH and glucose/insulin ratio > 0.3 indicates that surgical treatment with pancreatectomy should not be delayed.

Key words: Hypoglycemia, Hyperinsulinism.


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>Journals >Cirugía y Cirujanos >Year 2004, Issue 5

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