Revista Mexicana de Cirugía Bucal y Maxilofacial

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>Journals >Revista Mexicana de Cirugía Bucal y Maxilofacial >Year 2016, Issue 3

Figueroa FNP, Meraz AHF, Navarro EME, Serafín HNA, Beltrán PEA, Isiordia EMA
Assessment of maternal and environmental risk factors associated with cleft lip and palate during the first trimester of pregnancy
Rev Mex Cir Bucal Maxilofac 2016; 12 (3)

Language: Español
References: 30
Page: 93-98
PDF: 174.54 Kb.

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Aim: The objective of this study was to assess the risk of cleft lip with or without cleft palate in newborns according to different maternal and environmental risk factors during the first trimester of pregnancy. Patients and methods: A cases controls study was done in the clinic 31 of the Mexican Social Security Institute in Mexicali, Baja California, Mexico, prior authorization of the Internal Ethics Committee. A survey was applied each mother to evaluate the maternal and environmental risk factors previously reported in the literature. The risk evaluation was performed by calculating odds ratios with confidence intervals of 95% and statistical difference when p ‹ 0.05. Results: An increased risk for development cleft lip and palate was obtained for alcohol consumption and contact with chemicals (p ‹ 0.05). Conclusion: The results of this study suggest that alcohol consumption and contact with chemical agents during the first trimester of pregnancy increase the risk of developing cleft lip and palate.

Key words: Cleft lip and palate, maternal risk factor, environmental risk factor, alcohol consumption, use of chemicals.


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>Journals >Revista Mexicana de Cirugía Bucal y Maxilofacial >Year 2016, Issue 3

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