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>Journals >Revista de la Facultad de Medicina UNAM >Year 2015, Issue 4

Maldonado MMG, Pereyra MMA, Zenteno GEA
Structure and function of the alpha-fetoprotein
Rev Fac Med UNAM 2015; 58 (4)

Language: Español
References: 40
Page: 5-13
PDF: 226.65 Kb.

Full text


Alpha-fetoprotein is a glycoprotein that has been considered an oncofetal marker and demonstrated its application in tumor diagnosis and prognosis of diseases such as hepatocellular carcinoma, is also useful to identify fetal malformations related to failure of neural tube closure and anencephaly. There are several works that make an interesting relationship between the structure and function of this protein that allows it to regulate the immune response of the mother and could participate in events that prevent rejection of the embryo. In this review some molecular aspects of alpha-fetoprotein that open interesting perspectives to better understand their participation in the development of tumor abnormalities are identified.

Key words: Alpha-fetoprotein, hepatocellular, lectins.


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>Journals >Revista de la Facultad de Medicina UNAM >Year 2015, Issue 4

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