2018, Number 4
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ABSTRACTThe knowledge about the ontogeny of non-Hodgkin’s lymphomas has allowed to specify and separate some groups of non-Hodgkin’s lymphomas in terms of lineage, location, clinical, genetic and molecular characteristics among others. Undoubtedly, an approach to the lineage has contributed to improve response rates and survival, discriminating specific histological varieties, which also rule the therapeutic behavior based on its natural evolution, thus defining different treatment modes with results that seek different objectives, among the best known, disease-free survival, free time to new treatment or increase in overall survival. It is essential to use different tools, from natural history, sites of presentation, histological characteristics, immunohistochemical markers, diagnostic protocols with these markers that favor a more accurate reproducibility and diagnostic approach. Likewise, the discernment of the different most frequent subgroups of LNH lineage B favors the optimization of the results when diagnosing and treating with greater precision, this document addresses the non-Hodgkin’s lymphomas of B phenotype that we consider most frequent in our group, among those: diffuse large cells lymphoma, follicular, small lymphocytes, marginal zone, mantle, MALT and Burkitt lymphoma. Finally, some of the varieties can present themselves in a primary form in different specific locations at gastric or the central nervous system that force to establish precise treatments in these sites of presentation of the non-Hodgkin’s lymphomas.
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