2004, Number 2
Association between antibodies against porcine reproductive and respiratory syndrome virus and other pathogens
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ABSTRACTIn order to investigate a possible association between porcine reproductive and respiratory syndrome virus (PRRSV) and other viral and bacterial pathogenic agents found in swine, a serological model was followed. For this study, 3600, 4 to 6 month-old finishers were bled and tested for antibodies against various infectious agents. The specific antibodies against PRRSV, Aujeszky’s disease virus (ADV), transmissible gastroenteritis virus (TGEV), porcine respiratory coronavirus (PRCV) and Mycoplasma hyopneumoniae (MH) were detected by ELISA tests. For the blue eye disease virus (BEDV) and porcine parvovirus ( PPV), a hemoagglutination inhibition test was used. The microagglutination test was employed to determine antibodies against 11 serovars of Leptospira interrogans, while for Salmonella spp and Actinobacillus pleuropneumoniae serotype 1 (AP) the slide agglutination test was used. Antibodies against swine influenza virus (SIV) were detected by double diffusion test. The association between PRRSV and other microorganisms was evaluated by calculating the odds ratio (OR) and 95% confidence intervals (CI). In finishers, association was found between PRRSV and SIV (OR = 5.8, CI 95% 2.38, 14.55), PRCV (OR = 9.0, CI 95% 1.22, 82.53), and BEDV (OR = 2.95, CI 95% 1.16, 7.50). In 1 000 sows, association between PRRSV and SIV was found (OR = 3.54, CI 95% 1.29, 10.20), BEDV (OR =1.86, CI 95% 1.16, 3.00) and ADV (OR = 2.28, CI 95% 1.64, 3.18 ). No association between PRRSV infection and infection with TGEV, Salmonella spp, MH, AP or any of the leptospiral serovars was found.
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