2018, Number 4
Variability of arterial and peripheral venous blood gases parameters in subjects with stable obstructive pulmonary disease
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ABSTRACTBackground: Peripheral venous blood gases may be useful in subjects with exacerbation of chronic obstructive pulmonary disease to evaluate their gas exchange.
Objective: To describe the variability of parameters of arterial and peripheral venous blood gases in subjects with stable obstructive pulmonary disease.
Methods: Cross-sectional design, consecutive subjects were studied in a blinded manner, while arterial and peripheral venous blood was obtained for analysis. Variability was established with Bland-Altman statistical method and its magnitude with the intraclass correlation coefficient (95 % confidence interval).
Results: Three hundred blood samples from 150 patients were studied, 89 (59.3%) women, age 66 ± 10 years old, body mass index 28.44 ± 4.81 Kg/m2. Mean difference (bias) [intraclass correlation coeficient] pH 0.012 (-0.009, 0.032) [0.927], Carbon dioxide pressure - 6.5 (-14.1, 1.1) [ 0.643], serum bicarbonate -1.3 (-3.3, 0.7) [0.929], base excess -1 (-4, 2.1) [0.904], hemoglobin -0.1 (-1.9, 1.8) [0.947].
Conclusions: The variability of pH, serum bicarbonate, and hemoglobin are similar in both blood samples. These arterial or peripheral venous blood gas parameters could be used interchangeably.
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