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>Journals >Acta Pediátrica de México >Year 2013, Issue 3


Arellano-Penagos M, Aranda-Patrón E, López-Sotomayor LL
Pertussis: clinical and bacteriological diagnosis of six cases
Acta Pediatr Mex 2013; 34 (3)

Language: Español
References: 40
Page: 127-131
PDF: 192.12 Kb.


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ABSTRACT

Pertussis is an endemic disease in our population. Every 3 to 4 years, pertussis has an epidemic pattern even in countries with good health conditions. Antipertussis vaccine first dose is administered at the age of 2 months; a second and third dose are given at 4 and 6 months of age. This vaccine has an 8 to 10 year protective effect, for which reason it is suggested that pregnant women in the third trimester should be vaccinated in order to prevent pertussis in newborns. It should also be administered to older people to avoid turning them into asymptomatic carriers. Clinic manifestations are easily identifiable due to respiratory symptoms, especially to the particular characteristics of the cough. The diagnosis is supported by the presence of leukocytosis (predominantly lymphocytes) and by certain thoracic radiologic findings. The diagnosis is confirmed with a positive culture for Bordetella pertussis or with a polymerase chain reaction (PCR). In a non complicated clinic course macrolides are still the best therapeutic choice. Nonetheless clinic observation is highly recommended in order to avoid complications. Redefinition of vaccine programs against Bordetella pertussis in Mexican population is recommended and also to notify the presence of the disease to the corresponding health authorities.


Key words: Pertussis, Bordetella pertussis, antipertussis vaccine, lymphocytes, leukocytes, polymerase chain reaction (PCR).


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>Journals >Acta Pediátrica de México >Year 2013, Issue 3
 

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