Entrar/Registro  
HOME SPANISH
 
Cirujano General
   
MENU

Contents by Year, Volume and Issue

Table of Contents

General Information

Instructions for Authors

Message to Editor

Editorial Board






>Journals >Cirujano General >Year 2010, Issue 3


Rojas-Rueda D, Hernández-García AD, Sánchez-Obregón RA
Cyanoacrylate: hemostatic in hepatic trauma. Experimental study in an animal model
Cir Gen 2010; 32 (3)

Language: Español
References: 11
Page: 170-174
PDF: 4. Kb.


Full text




ABSTRACT

Objective: To establish the feasibility and efficacy of cyanoacrylate as a hemostatic agent in traumatic hepatic lesions.
Setting: Department of Experimental Surgery, School of Medicine, University of Guanajuato.
Design: Experimental, longitudinal, prospective study in an animal model.
Statistical analysis: Univariate analysis.
Material and methods: We performed a laparotomy in 10 dogs and performed two differently deep lesions using a surgical blade. We employed cyanoacrylate in the lesions sites to achieve hemostasis and tissue bonding. A second laparotomy was performed one week later for macroscopic evaluation and for biopsy sampling of the lesions.
Results: Hemostasis was obtained in all experimental animals and each of the lesions. One animal died due to causes unrelated to the surgery. Bonding of the tissue borders was also satisfactory in all lesions. Two animals formed adherences but only one at the lesion site. There were no cases of infection. The histopathological study revealed no microscopic evidence of the adhesive 7 days after its use.
Conclusions: Ethyl cyanoacrylate is an effective tissue adhesive useful to promote hemostasis and sealing of the hepatic parenchyma in penetrating trauma in the animal model. It is a well-tolerated, effective, easily applied and low cost agent.


Key words: Cyanoacrylates, hemostasis, liver, trauma.


REFERENCIAS

  1. González-Castro A, Suberviola CB, Holanda PMS, Ots E, Domínguez AMJ, Ballesteros MA. Liver trauma. Description of a cohort and evaluation of therapeutic options. Cir Esp 2007; 81: 78-81.

  2. Feliciano DV, Mattox KL, Jordan GL, Jr., Burch JM, Bitondo CG, Cruse PA. Management of 1,000 consecutive cases of hepatic trauma (1979-1984). Ann Surg 1986; 204: 438-445.

  3. Biondo-Simoes Mde L, Petrauskas R, Dobrowolski AG, Godoy G, Kaiber F, Ioshii SO. Validity of microporous polysaccharide hemispheres as a hemostatic agent in hepatic injuries: an experimental study in rats. Acta Cir Bras 2007; 22 (Suppl 1): 29-33.

  4. Dávila-Serapio F, Islas-Muñoz HG, Carbonell CJM, Hernández GLM, Sánchez GDJ, Rivera CJM. Uso del 2 cianoacrilato de N-butilo en la reparación primaria de heridas penetrantes en hígado, bazo e intestino delgado: modelo experimental en perros. Rev Sanid Milit 2009; 63: 182-188.

  5. Singer AJ, Quinn JV, Hollander JE. The cyanoacrylate topical skin adhesives. Am J Emerg Med 2008; 26: 490-496.

  6. Leggat PA, Smith DR, Kedjarune U. Surgical applications of cyanoacrylate adhesives: a review of toxicity. ANZ J Surg 2007; 77: 209-213.

  7. Escalante-Pina O, García-Nieto G, Hernández-Jasso AR, Reyes-Castellanos L, Flores-Aragón M, Rivera-Cruz JM. Adhesivo tisular 2-octil cianoacrilato en el cierre de enterotomía comparado con sutura manual tradicional en dos capas. Modelo en perros. Cir Cir 2009; 77: 121-125.

  8. Yoo J, Chandarana S, Cosby R. Clinical application of tissue adhesives in soft-tissue surgery of the head and neck. Curr Opin Otolaryngol Head Neck Surg 2008; 16: 312-317.

  9. Stutts JC, Williamson JE, Whitley T, Sheldon FC. Bicycle accidents and injuries: a pilot study comparing hospital- and police-reported data. Accid Anal Prev 1990; 22: 67-78.

  10. Quinn J, Wells G, Sutcliffe T, Jarmuske M, Maw J, Stiell I, et al. A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations. JAMA 1997; 277: 1527-1530.

  11. de Blanco LP. Lip suture with isobutyl cyanoacrylate. Endod Dent Traumatol 1994; 10: 15-18.






>Journals >Cirujano General >Year 2010, Issue 3
 

· Journal Index 
· Links 






       
Copyright 2019