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>Journals >Cirujano General >Year 2001, Issue 3


Martínez MG, Toledo-Pereyra LH
Charles Brenton Huggins: Surgeon, scientist, and Nobel Laureate
Cir Gen 2001; 23 (3)

Language: Español
References: 14
Page: 194-203
PDF: 4. Kb.


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ABSTRACT

Objective: Narrate life and legacy of Charles Brenton Huggins.
Design: Historic essay (14 references).
Setting: University Department of History.
Results: Charles Brenton Huggins was born in Canada on September 22, 1901. He graduated as Bachelor in Arts from Acadia University and obtained his MD degree from Harvard University in 1924. He received his surgical training at University of Michigan and was appointed instructor in surgery at the University of Chicago in 1927, where he performed the rest of his professional activity. Huggins showed the sexual hormone influences over the glandular activity of the prostate and described orchiectomy as a treatment for prostate carcinoma with excellent results. As a scientist, Huggins expanded the horizon of the hormonal therapy against different tumors such as breast cancer. He studied the cellular transformation phenomenon, calcium metabolism and developed animal models for oncologic diseases as the Director of the Ben May Institute for Cancer Research and Professor of Surgery at the University of Chicago. Surgeon, researcher, husband and father, Huggins was an extremely dedicated man to his scientific mission without pause and rest; moreover, he created a multidisciplinary school of scientists to the service of medicine and science. He was awarded with multiple medals and prizes, including the Nobel Prize of Physiology and Medicine in 1966. He died on January 12, 1997, being his life and example a model and stimuli for the following generations.


Key words: Huggins, surgery, Nobel Prize.


REFERENCIAS

  1. Martínez Mier G, Toledo-Pereyra LH. Werner Theodor Otto Forssmann: cirujano cateterista y Premio Nobel. Cir Gen 2000; 22: 257-63

  2. Nobel Lectures, Physiology or Medicine, 1963-1970. Amsterdam: Elsevier Publishing Company, 1970.

  3. Forster RE. Charles Brenton Huggins. Proc Am Phylos Soc 1999; 43: 327-331.

  4. Jain KM, Swan KG, Casey KF. Nobel Prize Winners in Surgery. Am Surg 1982; 48: 495-500.

  5. Rappaport MG. Tales from the Forefront. A Tribute to the Life and Times of Charles Brenton Huggins, MD. Medicine on the Midway. Chicago: University of Chicago Press, 1997.

  6. Rutkow IM, Burns Stanley B. American History: an illustrated history. Philadelphia: Lippincott-Raven Publishers, 1998.

  7. Toledo-Pereyra LH. Maestros de la cirugía contemporánea. México: JGH Editores;1999.

  8. Morris JB, Schirmer WJ. The “right stuff”: five Nobel Prize-winning surgeons. Surgery 1990; 108: 71-80.

  9. Huggins CB. The business of discovery in the medical sciences. JAMA 1965; 194: 1211-5.

  10. Classics in Oncology. Charles Brenton Huggins. CA Cancer J Clin 1972; 22: 230-1.

  11. Drucker WR. Charles B. Huggins, MD, FACS (hon). Surg Forum 1973; 24: V.

  12. Raju TN. The Nobel chronicles. 1966: Francis Peyton Rous (1879-1970) and Charles Brenton Huggins (1901-1907). Lancet 1999; 354: 520.

  13. Huggins CB. On medical investigation. Surg Clin North Am 1969; 49: 455-7.

  14. Division of Biological Sciences. The University of Chicago. Charles Brenton Huggins, MD, Nobel Laureate Physioloy and Medicine 1966. Chicago: University of Chicago Press, 1966.






>Journals >Cirujano General >Year 2001, Issue 3
 

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