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>Journals >Revista Biomédica >Year 2003, Issue 4


Martín-Hernández I, García-Izquierdo SM
Prevalence of IgG antibodies against Toxoplasma gondii in Cuban blood donors
Rev Biomed 2003; 14 (4)

Language: Español
References: 21
Page: 247-251
PDF: 32.46 Kb.


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ABSTRACT

Introduction. Toxoplasmosis is a human infection disease that occurs worldwide and its frequency varies among different geographical zones and eating habits. In Cuba this infection is common, although the presence of specific antibodies varies between 50-75% in relation with the geographical area and the detection method employed.
Materials and methods. A seroepidemiological study of 922 blood donors’ serum samples from the Municipality of Marianao, Havana City, was carried out with the purpose of measuring concentrations of anti-T. gondii IgG antibodies (UI/mL) and the behaviour of seropositivity with age. The heterogeneous immunoenzimatic assay UMELISA Toxoplasmaâ was used for the detection of IgG antibodies to Toxoplasma gondii in serum samples.
Results. A seroprevalence to Toxoplasma gondii of 73,43% was found, additionally an increase in seropositivity with age and a decrease of reactivity percentages with the increase of titles were observed. The presence of specific IgG antibodies showed similar behaviour for the age groups 20-24, 25-29, and 30-34 years old with no significant difference between them (p›0,05). In the same way, they differ significantly (p‹0,05) from to 35-39 and 40-or more year old age groups, although these age groups showed no difference between each other.
Discussion. The high prevalence of anti-Toxoplasma gondii IgG antibodies in the Municipality of Marianao lead us to consider this province as an intensive endemic zone.


Key words: Toxoplasma gondii, IgG antibodies, UMELISA, blood donors.


REFERENCIAS

  1. Kasper LH. Toxoplasma infection. En: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, editores. Harrinson’s Principles of Internal Medicine. 15 edition. New York: McGraw-Hill 2001. p. 1222-7.

  2. Acosta C, Pérez X, García R. Presencia de anticuerpos IgG anti-Toxoplasma gondii en embarazadas residentes en Ciudad de la Habana. Rev Biomed 2001; 12: 250-4.

  3. González T, Bacallao J, García C, Molina JR. Prevalencia de anticuerpos anti-Toxoplasma gondii en una población de mujeres embarazadas en Cuba. Gac Méd Méx 1991; 131: 499-03.

  4. Collazo JE, López R, Ginorio D, Llamos R, Contreras R. Anticuerpos IgG anti-Toxoplasma gondii en pacientes con síntomas atribuíbles a toxoplasmosis. Biomed 1993; 13:179-82.

  5. Martinez R, Bacallao R, Alberti E, Alfonso I. Prevalence of toxoplasmosis in pregnant women of the province of La Habana. Rev Inst Trop Sao Paulo 1994; 36: 445-50.

  6. Delgado G. A Cuban bibliography of toxoplasmosis II (1971-1980). Rev Cub Med Trop 1982; 34: 160-71.

  7. López R, Fano R, Contreras R, Font L. Anticuerpos IgG anti- Toxoplasma gondii en cubanos donantes de sangre. Rev Lat Amer Microbiol 1993; 35: 207-10.

  8. Thulliez Ph, Derouin F, Peyron F, Wallon M, Candolfi E. Toxoplasmosis and diagnostic. 1a ed. Madrid: Coimpress SA; 1996. p. 11.

  9. Sánchez A, Martín I, García S. Estudio de reactividad a Toxoplasma gondii en embarazadas de las provincias Ciudad de la Habana y Pinar del Río, Cuba. Bioquimia 2003; 111: 3-8.

  10. Góngora-Biachi RA, González-Martínez P, Castro- Sansores C, Álvarez-Moguel R, Pavía-Ruz N, Lara-Perera D, et al. Anticuerpos contra Toxoplasma gondii en pacientes con VIH en Yucatán. Rev Invest Clin 1998; 50: 419-22.

  11. Hirt J, Kaufer F, Carral L, Durlach R, Schmee E. Estudio comparativo de la prevalencia de la infección toxoplásmica en la ciudad de Buenos Aires entre los años 1967 y 1992. VI Congreso Panamericano de Infectología, 26-29 Mayo de 1993, Viña del Mar, Chile.

  12. Bahía LM, Jones JL, Azevedo J, Alves CC, Orefice F, Dais DG. Highly endemic waterborne toxoplasmosis in North Rio de Janeiro state, Brasil. Emerg Infect Dis 2003; 9: 55-62.

  13. Orefice F, Bonfioli AA. Toxoplasmose. En: Orefice F, editor. Uveite clinica e cirugica. Rio de Janeiro: Editora Cultura Médica; 2000. p. 619-80.

  14. Arias L, Chinchilla M, Reyes L, Linder E. Seroepidemiology of transmission humans: posible transmisión routes in Costa Rica. Rev Biol Trop 1996; 44: 377-81.

  15. Wallace GD. Serologic and epidemiologic observations on toxoplasmosis on three Pacific atolls. Am J Epid 1969; 90: 103-11.

  16. Machín R, Martínez R, Fachado A, Pividal J, Cruz R. Encuesta Nacional de Toxoplasmosis. Resumen: 50. Aniversario Inst. Med. Tropical “ Pedro Kourí 1988; 134.

  17. Acosta C, Pérez X, Herrera R, Solís RL, López R, Machín R, et al. Evaluación clínica del UMELISA Toxoplasma. Congreso “Biotecnología Habana 92” 1992.

  18. Foulon W, Naessens A, Lauwer S. Impact of primary prevention on the incidence of toxoplasma during pregnancy. Obstet Gynecol 1988; 72: 363.

  19. Jackson MH, Hutchison WN. A seroepidemiological survey of toxoplasmosis in Scotland and England. Ann Trop Med Parasit 1987; 81: 360.

  20. Logar J, Novak-Antolic Z, Zore A, Cerar V, Likar M. Incidence of the congenital toxoplasmosis in the Republic of Slovenia. Scand J Infect Dis 1992; 24: 105-8.

  21. Remington JS, McLeod R, Desmonts G. Toxoplasmosis. En: Remington JS, Klein JO, editores. Infectious diseases of the fetus and newborn infants. 5th edition. Philadelphia: W.B. Saunders Company; 2001. p. 205-346.






>Journals >Revista Biomédica >Year 2003, Issue 4
 

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