Table 1: Diagnostic criteria for acute cholecystitis according to the Tokyo 18 guidelines.

A. Local signs of inflammation

1. Murphy’s sign

2. Pain/mass/tenderness in URQ

B. Signs of systemic inflammation

1. Fever

2. CPR increased

3. White blood cell counts increased

C. Image study findings

Characteristic findings of acute cholecystitis*

Diagnostic suspicion:

one element of A + one element of B

Definitive diagnosis:

one element of A + one element of B + C

URQ = upper right quadrant;

CPR = C-reactive protein.

* Imaging findings: thickening of the vesicular wall, peri-vesicular fluid, positive Murphy’s sonographic sign.