Table 1: Medication use and comorbidities.

Variable

SpA + EDS

%

EDS-only

%

p

Biologic use

34.8

7.1

0.05

Immunomodulator use

73.9

42.8

0.003

NSAID use

30.4

47.4

> 0.05

MCAS

13.0

85.7

< 0.0001

POTS/dysautonomia

60.9

78.6

> 0.05

IBS/digestive disorders

60.9

85.7

> 0.05

Upper cervical instability

17.5

21.4

> 0.05

EDS = Ehlers-Danlos syndromes.

IBS = irritable bowel syndrome.

MCAS = mast cell activation syndrome.

NSAID = nonsteroidal anti-inflammatory drugs.

POTS = postural orthostatic tachycardia syndrome.

SpA = spondyloarthritis.