2010, Number 6
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Rev Med Inst Mex Seguro Soc 2010; 48 (6)
Changes on craniofacial structures in children with growth-hormone-deficiency
Salas-Flores R, González-Pérez B, Barajas-Campos RL, Gonzalez-Cruz B
Language: English
References: 23
Page: 591-595
PDF size: 34.74 Kb.
ABSTRACT
Objective: to describe the growth of craniofacial
structures in growth-hormone deficiency (GHD)
children during growth-hormone therapy (GHT).
Methods: a cross-sectional sample of 46 subjects
(
n = 14 girls, 32 boys) aged 4-18 years was obtained.
They were categorized into two paired
groups: the reference group, for comparing the
cephalograms, consisted in 23 healthy subjects,
and the study group (23 patients) with GHD under
GHT. Differences between groups were assessed
by independent t-tests.
Results: the boys showed smaller measurements
for all facial structures presenting significant differences
in total mandibular length (Co-Pg
p ‹ 0.03),
lower anterior facial height (ANS-Me p ‹ 0.03) and
total anterior facial height (N-Me p ‹ 0.02) as well
as retrognathic facial type. In girls the posterior
cranial base length was shortened (S-Ba 29.14 ±
3.02 mm) and show a high mandibular plane angle
(40 ± 5.50º) a wide relation anterior maxillo-mandibular
(5.86 ± 1.57º) with a statistical difference
(
p ‹ 0.05 and
p ‹ 0.04) compared with the reference
group.
Conclusions: we suggest considering the cephalometric
morphology at the beginning of GHT.
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