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Instituto Nacional de Salud Pública

2022, Número 3

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salud publica mex 2022; 64 (3)


Seguimiento serológico de casos positivos a SARS-CoV-2

González-González JG, Camacho-Ortiz A, Rodríguez-Gutiérrez R, Saldívar-Rodríguez D, Ramírez-García LA, Sánchez-García A

Idioma: Ingles.
Referencias bibliográficas: 28
Paginas: 243-248
Archivo PDF: 278.02 Kb.


RESUMEN

Objetivo. Describir la respuesta humoral en una cohorte con una infección leve o asintomática por SARS-CoV-2, previamente identificada en una encuesta serológica comunitaria. Material y métodos. Se realizó un seguimiento observacional de 193 individuos previamente identificados con anticuerpos IgM/IgG anti-SARS-CoV-2 invitados 112 días después de una determinación serológica inicial. Todos los participantes completaron un cuestionario electrónico estandarizado. Se determinaron los anticuerpos IgM/IgG mediante un inmunoensayo quimioluminiscente cualitativo. Resultados. De entre los 193 sujetos elegibles, 174 (90%) acudieron al seguimiento. De las muestras, 171 (98.3%) eran positivas y 3 (1.7%) negativas. Además, el valor de COI del inmunoenasayo se incrementó al comparar la primera y segunda determinación (P ‹0.001). Conclusiones. Los presentes resultados apoyan una respuesta humoral sostenida en individuos con infección por SARS-CoV-2 con síntomas leves o asintomática hasta 112 días después de una prueba serológica positiva, acompañada de incremento en los títulos de anticuerpos.


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