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ISSN 0185-3252 (Impreso)
Revista de la Asociación Médica del Centro Médico ABC

2022, Número 2

An Med Asoc Med Hosp ABC 2022; 67 (2)


Nanomedicina y nanopartículas en una nueva era oncológica

Shveid GD, Shalkow KJ

Idioma: Ingles.
Referencias bibliográficas: 26
Paginas: 131-136
Archivo PDF: 235.54 Kb.


RESUMEN

El cáncer es un reto de la salud global. La nanotecnología y la nanomedicina, la síntesis y uso de materiales con dimensiones en escalas atómicas o moleculares (diámetros de ≤ 100 nm), se han utilizado cada vez más en la medicina y se consideran de gran importancia en cuanto a su capacidad de matar microorganismos o su papel en la transformación de células neoplásicas. Estas partículas exhiben características únicas debidas a su alta tasa de volumen a área de superficie con propiedades químicas y físicas únicas. En la investigación contemporánea se puede apreciar esta nueva tecnología para el diagnóstico de cáncer y su tratamiento. Estudios que involucran a las nanopartículas incluyen vehículos para administración directa de medicamentos, modulación de interacciones entre medicamentos y el sistema inmune, activación de blancos terapéuticos con mejor retención y recepción de drogas, nanopartículas que contienen agentes terapéuticos y de imagen que permiten la detección selectiva de células neoplásicas a través de técnicas de imagen en tiempo real hasta la detección de células neoplásicas mediante biopsia líquida dirigida por nanopartículas de exosomas. Sin duda, esta frontera en la oncología moderna requiere de una revisión que permita conocer nuevas herramientas en el diagnóstico y tratamiento de neoplasias.


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