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2022, Número 4

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Rev Cubana Hematol Inmunol Hemoter 2022; 38 (4)


Caracterización fisiopatológica de las anemias hemolíticas autoinmunes

Soler NG

Idioma: Español
Referencias bibliográficas: 55
Paginas: 1-22
Archivo PDF: 690.69 Kb.


RESUMEN

Introducción: La anemia hemolítica autoinmune se define como el aumento de la destrucción de los eritrocitos en presencia de autoanticuerpos dirigidos contra antígenos de grupos sanguíneos eritrocitarios.
Objetivo: Caracterizar las anemias hemolíticas autoinmunes teniendo en cuenta las características fisiopatológicas, manifestaciones clínicas y el diagnóstico de laboratorio.
Métodos: Se realizó una revisión de la literatura en inglés y español de artículos publicados en los últimos 10 años sobre anemia hemolítica autoinmune.
Conclusiones: La anemia hemolítica autoinmune es una enfermedad muy heterogénea. El diagnóstico suele ser fácil, pero los casos difíciles pueden ser un desafío. La definición de cada tipo es fundamental ya que la terapia es diferente y se enfoca más con la comprensión de los mecanismos patogénicos.


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