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>Revistas >Gaceta Médica de México >Año 2009, No. 4


Chávez-Galán L, Arenas-Del Ángel MC, Sada-Ovalle I, Lascurain R
Principales mecanismos de evasión de la respuesta inmune por Mycobacterium tuberculosis
Gac Med Mex 2009; 145 (4)

Idioma: Español
Referencias bibliográficas: 91
Paginas: 323-330
Archivo PDF: 157.44 Kb.


Texto completo




RESUMEN

En la actualidad, la tuberculosis pulmonar es considerada un problema grave de salud mundial. Para entender el proceso infeccioso de la tuberculosis es necesario conocer las interacciones entre la respuesta inmune del hospedero y su agente causal. Actualmente se han realizado grandes avances en la identificación de nuevas moléculas y genes que participan activamente en los mecanismos de evasión, generando la posibilidad de que en un futuro próximo se diseñen diversos compuestos químicos para el desarrollo de vacunas o terapias que tengan como blanco estas moléculas o genes. Sin embargo, no se han esclarecido completamente los diversos mecanismos con que cuenta la micobacteria para evadir la respuesta inmune del hospedero. En esta revisión se discute la evidencia experimental reciente sobre los mecanismos propuestos para el éxito de la bacteria.


Palabras clave: Mycobacterium tuberculosis, evasión respuesta inmune, tuberculosis.


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>Revistas >Gaceta Médica de México >Año2009, No. 4
 

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