Escobedo-Cousin MH, Madrigal JA

Idioma: Español
Referencias bibliográficas: 17
Paginas: 82-85
Archivo PDF: 62.94 Kb.

RESUMEN

Las células madre habitan en un microambiente altamente regulado mediante interacciones celulares y bajo la influencia de factores solubles, como: citocinas, quimocinas, hormonas, entre otros. En años recientes, diferentes grupos se han dedicado a investigar la interacción de las células madre con su nicho, estudiando los mecanismos de regulación y las interacciones entre las células madre y las células que conforman el nicho. En este artículo exponemos de manera breve el entendimiento que se tiene hasta la fecha de la interacción de las células madre y su nicho.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Kollet OA Dar, Lapidot T. The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization. Annual review of Immunology 2007;25:51-69.

2. Lapidot TA, Dar and O Kollet. How do stem cells find their way home? Blood 2005;106(6): 1901-1910.

3. Kucia M, Reca R, Miekus K, et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem cells 2005; 23(7):879-894.

4. Lee Y, Gotoh A, Kwon HJ, et al. Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines. Blood 2002;99(12):4307-4317.

5. Avigdor A, Goichbrg P, Shivitel S, et al. CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow. Blood 2004;103(8):2981-2989.

6. Peled A, Grabovsky V, Habler L, et al. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow. J Clinical Investigation 1999;104(9):1199-1211.

7. Peled A, Kollet O, Ponomaryov T, Petit I, et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood 2000;95(11):3289-3296.

8. Nagasawa T, Hirota S, Tachibana K, et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1996;382(6592):635-638.

9. Peled A, Petit I, Kollet O, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999;283(5403):845-848.

10. Schofield R. The relationship between the spleen colonyforming cell and the haemopoietic stem cell. Blood cells 1978;4(1-2):7-25.

11. Xie Y, Yin T, Wiegraebe W, et al. Detection of functional haematopoietic stem cell niche using real-time imaging. Nature 2009;457(7225):97-101.

12. Lo Celso C, Fleming HE, Wo JW, et al. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature 2009;457(7225):92-96.

13. Grassinger J, Haylock DN, Williams B, Olsen GH, Nilsson SK. Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential. Blood 2010;116(17):3185-3196.

14. Winkler IG, Sims NA, Pettit AR, et al. Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood 2010;116(23):4815-4828.

15. Weber JM, Forsythe SR, Christianson CA, et al. Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells. Bone 2006;39(3):485-493.

16. Porter RL, Calvi LM. Communications between bone cells and hematopoietic stem cells. Arch Biochemistry Bioph 2008;473(2):193-200.

17. Mendez-Ferrer S, Lucas D, Battista M, Frenette P. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 2008;452(7186):442-447.