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2011, Número 4

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Med Sur 2011; 18 (4)


¿Somos tan viejos como nuestros linfocitos? Inmunosenescencia

Ledesma-Heyer JP, Valdés-Escárcega M, Ramos-Ostos MH
Texto completo Cómo citar este artículo Artículos similares

Idioma: Español
Referencias bibliográficas: 46
Paginas: 168-173
Archivo PDF: 81.29 Kb.


PALABRAS CLAVE

Inmunosenescencia, Envejecimiento, Timo, NF-κβ, Inflammaging.

RESUMEN

La inmunosenescencia es un tipo de inmunodeficiencia adquirida idiopática resultado de cambios celulares y moleculares propios del envejecimiento. En el presente artículo se revisarán los principales cambios a nivel del timo y de las respuestas innata y adquirida de la inmunidad. Asimismo, se comentarán algunas teorías del envejecimiento inmunológico. Diversas enfermedades propias de la vejez (infecciones, cáncer, crónico-degenerativas, osteoporosis, etc.) tienen su origen en el sistema inmune envejecido.


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