Rojas RGA, Sarue SN, Hernández VFX, Velazco JS, Villalobos PA

Idioma: Español
Referencias bibliográficas: 15
Paginas: 23-27
Archivo PDF: 487.67 Kb.

RESUMEN

La púrpura fulminante es una enfermedad catastrófica caracterizada por la aparición súbita de lesiones hemorrágicas cutáneas, que rápidamente se esparcen y coalescen hasta progresar a gangrena. Este proceso se asocia a una extensa trombosis intravascular a nivel capilar. Presentamos un caso de púrpura fulminante posquimioterapia y sepsis por Escherichia coli

REFERENCIAS (EN ESTE ARTÍCULO)

1. Torres R, Ballona R. Púrpura fulminans asociada a defi ciencia de proteína C, proteína S y resistencia a proteína C activada. Dermatol Pediatr 2005; 16: 33 7.

2. Betrosian A, Berlet T. Purpura fulminans in sepsis. Am J Med Sci 2006; 33: 339 45.

3. Gast T, Kowal Vern A, An G, et al. Purpura fulminans in an adult patient with Haemophilus influenzae sepsis: case report and review of the literature. J Burn Care Res 2006; 27: 102 7.

4. Davis M, Dy K, Nelson S. Presentation and outcome of pur pura fulminans associated with peripheral gangrene in 12 patients at Mayo Clinic. J Am Acad Dermatol 2007; 57: 944 56.

5. Nolan J, Sinclair R. Review of management of purpura ful minans and two case reports. Br J Anaesth 2001; 86: 581 6.

6. Villavicencio JL, González Cerna JL, Velasco P. Acute vas cular problems of children. In: Ravitch M, Steichen F, Aus ten WG, Scott HW (eds.). Current Problems in Surgery. Vol. 22. Chicago ILL. USA: Year Book Medical Publishers; 1985, p. 58 64.

7. Frutos MC, Iturrioz MA., González PYE, Arratibel FM, et al. Púrpura fulminante idiopática con déficit transitorio de proteína S. An Esp Pediatr 2001; 55: 369 73.

8. Manco Johnson M, Knapp Clevenger R. Activated protein C concentrate reverses Purpura fulminans in severe genetic protein C deficiency. J Pediatr Hematol Oncol 2004; 26: 25 7.

9. Rintala E, Kuppila M, Seppälä O, et al. Protein C substitu tion in sepsis associated purpura fulminans. Crit Care Med 2000; 28: 2373 8.

10. Perler BA. The effect of statin medications on perioperative and long term outcomes following carotid endarterectomy or stenting. Semin Vasc Surg 2007; 20: 252 8.

11. Almog Y, Terblanche M. Pleiotropic effects of statins: impli cations for critical care. Contemporary Critical Care 2008; 12: 1 11.

12. McGown CC, Brookes ZLS. Beneficial effects of statins on the microcirculation during sepsis: the role of nitric oxide. Br J Anaesth 2007; 98: 163 5.

13. Hassan Z, Mullins R, Friedman B, Shaver J, et al. Purpura fulminans: a case series managed at a regional burn center. J Burn Care Res 2008; 29: 411 5.

14. Andreasen T, Green S, Childers B. Massive Infectious Soft Tissue Injury: diagnosis and management of necrotizing fasciitis and Purpura fulminans. Plast Reconstr Surg 2001; 1(107): 1025 35.

15. Duteille F, Thibault F, Perrot P, et al. Salvaging limbs in cases of severe Purpura fulminans: advantages of free flaps. Plast Reconstr Surg 2006; 118: 681 5.