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2015, Número 2

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Rev Cubana Hematol Inmunol Hemoter 2015; 31 (2)


Síndrome de aglutininas frías y púrpura trombocitopénica autoinmune. Un caso inusual de síndrome de Evans

Alfonso VME, Bencomo HA, Hernández PC, Avila COM

Idioma: Español
Referencias bibliográficas: 32
Paginas: 195-203
Archivo PDF: 99.18 Kb.


RESUMEN

El síndrome de Evans es un trastorno poco frecuente en el que se observan trombocitopenia y anemia, ambas de etiología autoinmune; las que pueden ocurrir de manera simultánea o sucesiva. Se presenta un caso poco usual de anemia hemolítica autoinmune por anticuerpos fríos asociada a púrpura trombocitopénica autoinmune. Paciente femenina de 22 años de edad con diagnóstico de púrpura trombocitopénica autoinmune, después de 7 años de evolución y un año en remisión, presentó una anemia hemolítica autoinmune por anticuerpos fríos, refractaria al tratamiento con esteroides y alcaloides de la Vinca, que requierió transfusiones de concentrado de eritrocitos y logró la remisión con la administración de anticuerpo monoclonal anti CD 20. Los restantes estudios de autoinmunidad fueron negativos. Actualmente se mantiene asintomática y sin tratamiento inmunosupresor.


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