Chiquete AE, Sánchez OLV, Panduro CA

Idioma: Español
Referencias bibliográficas: 32
Paginas: 19-25
Archivo PDF: 256.93 Kb.

RESUMEN

El cuadro clínico que ahora conocemos como de hepatitis asociado a transmisión parenteral se reconoció hace más de 100 años. Se estima que esta infección por el virus de la hepatitis C (VHC) afecta a cerca del 3% de la población mundial. En México la prevalencia es de aproximadamente el 1%, dando cuenta de 1 millón de individuos afectados. La infección crónica por el VHC puede originar cirrosis hepática y eventualmente carcinoma hepatocelular. El tratamiento actual dista mucho de ser perfecto, obteniéndose con éste un 40% a 60% de eliminación del virus circulante, dependiendo del genotipo.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Bonkovsky HL, Mehta S. Hepatitis C: A review and update. J Am Acad Dermatol, 2001;44:159-79.

2. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derive from a blood-borne non-A, non-B viral hepatitis. Science, 1989;244:359-62.

3. Kuo G, Choo QL, Alter HJ, Gitnik GL, Redeker AG, Purcell RH, et al. An assay for circulating antibodies to a major etiologic virus of non-A, non-B hepatitis. Science, 1989;244:362-4.

4. Choo QL, Richman KH, Han JH, Berger K, Lee C, Dong C, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA, 1991;88:2452-5.

5. Memom MI, Memom MA. Hepatitis C: an epidemiological review. J Viral Hepat, 2002;9:84-100.

6. Conry-Cantilena C, VanRaden M, Gibble J, Melpolder J, Shakil AO, Viladomiu L, Cheung L, et al. Routs of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection. NEJM, 1996;334:1691-6.

7. Poynard T, Yuen MF, Ratziu V, Lai CL. Viral hepatitis C. Lancet, 2003;362:2095-3000.

8. Alter MJ, Kruszon-Moran D, Nainan OV, McQuillan GM, Gao F, Moyer LA, et al. The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. NEJM, 1999;341:556-62.

9. Méndez-Sánchez N, Aguilar-Ramírez JR, Reyes A, Dehesa M, Juárez A, Castañeda B, Sánchez-Ávila F, et al. Etiology of liver cirrhosis in Mexico. Ann Hepatol, 2004;3:30-33.

10. Méndez-Sánchez N, Sánchez-Ávila JF, Hernández-López VJ, Poo JL, Guevara-González L, Uribe M. Epidemiología e impacto sacial del virus de la hepatitis C. En: Méndez-Sánchez N, Uribe M. Conceptos actuales en hepatitis C. México, MCGraw-Hill-Interamericana. 2003. 1-17.

11. Vivas-Arceo C, Benavides SA, De Jesus Trujillo J, Panduro A, Rivas-Estilla AM. Hepatitis C virus: prevalence and routes of infection among blood donors of West Mexico. Hepatol Res, 2003;25(2):115-123.

12. Alter MJ, Kuhnert WL, Finelli L; Centers for Disease Control and Prevention. Guidelines for laboratory testing and result reporting of antibody to hepatitis C virus. Centers for Disease Control and Prevention. MMWR Recomm Rep, 2003;52(RR-3):1-13.

13. Kiely P, Kay D, Parker S, Piscitelli L. The significance of third-generation HCV RIBA-indeterminate, RNA-negative results in voluntary blood donors screened with sequential third-generation immunoassays. Transfusion, 2004;44:349-358.

14. Sookian S, Castaño G. Evaluation of a third generation anti-HCV assay in predicting viremia in patients with positive HCV antibodies. Ann Hepatol, 2002;4:179-178.

15. Simmonds P. Viral heterogeneity of the hepatitis C virus. J Hepatol, 1999;31(S1):54-60.

16. Zein NN. Clinical significance of hepatitis C virus genotypes. Clin Microbiol Rev, 2000;13:223-35.

17. Rosenberg S. Recent advances in the molecular biology of hepatitis C virus. J Mol Biol, 2001;313(3):451-64.

18. Kohara M. Hepatitis C virus replication and pathogenesis. J Dermatol Sci, 2000;(3):161-8.

19. Simmonds P. The origin and evolution of hepatitis viruses in humans. J Gen Virol, 2001;2:693-712.

20. Smith DB, Pathirana S, Davidson F, Lawlor E, Power J, Yap PL, Simmonds P. The origin of hepatitis C virus genotypes. J Gen Virol, 1997;78:321-8.

21. Pybus OG, Charleston MA, Gupta S, Rambaut A, Holmes EC, Harvey PH. The epidemic behavior of the hepatitis C virus. Science, 2001;292(5525):2323-5.

22. Vandelli C, Renzo F, Romano L, Tisminetzky S, De Palma M, Stroffolini T, Ventura E, et al. Lack of evidence of sexual transmission of hepatitis C among monogamous couples: results of a 10-year prospective follow-up study. Am J Gastroenterol, 2004;99(5):855-9.

23. Jones IM, Jiang WR, Clarke BE. Receptors for hepatitis C virus. J Virol, 2000;74(22):10860-1.

24. Agnello V, Abel G, Elfahal M, Knight GB, Zhang QX. Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. Proc Natl Acad Sci USA, 1999;96(22):12766-71.

25. Lauer GM, Walker BD. Medical Progress: Hepatitis C Virus Infection. NEJM, 2001;345:41-52.

26. Radkowski M, Wilkinson J, Nowicki M, Adair D, Vargas H, Ingui C, Rakela J, Laskus T. Search for hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: evidence of replication. J Virol, 2002;76(2):600-8.

27. Forton DM, Allsop JM, Main J, Foster GR, Thomas HC, Taylor-Robinson SD. Evidence for a cerebral effect of the hepatitis C virus. Lancet, 2001;(9275):38-9.

28. Casiraghi MA, De Paschale M, Romano L, Biffi R, Assi A, Binelli G, Zanetti AR. Long-term outcome (35 years) of hepatitis C after acquisition of infection through mini transfusions of blood given at birth. Hepatology, 2004;39(1):90-6.

29. Jara P, Resti M, Hierro L, Giacchino R, Barbera C, Zancan L, et al. Chronic hepatitis C virus infection in childhood: clinical patterns and evolution in 224 white children. Clin Infect Dis, 2003;36(3):275-80.

30. García-Monzón C, Jara P, Fernández-Bermejo M, Hierro L, Frauca E, Camarena C, et al., Chronic hepatitis C in children: A clinical and immunohistochemical comparative study with adult patients. Hepatology, 1998;28(6):1696-01.

31. Pawlotsky JM. Use and interpretation of virological tests for hepatitis C. Hepatology, 2002;36:S65-S73.

32. Baker DE. Pegylated interferon plus ribavirin for the treatment of chronic hepatitis C. Rev Gastroenterol Disord, 2003;3(2):93-109.