María CA, Porras VMG

Idioma: Inglés
Referencias bibliográficas: 23
Paginas: 27-31
Archivo PDF: 83.82 Kb.

RESUMEN

La alimentación al seno materno provee al recién nacido de una eficiente protección contra diferentes tipos de infecciones. Esta protección está mediada tanto por la presencia de anticuerpos y células inmunocompetentes, así como por factores bioactivos, tales como: oligosacáridos, enzimas, hormonas, factores de crecimiento y citocinas, que participan en la maduración de diferentes estirpes celulares. De los anticuerpos, la inmunoglobulina A representa la mayor proporción; esta inmunoglobulina secretora inhibe la traslocación de bacterias productoras de infecciones intestinales, evitando la bacteremia, la eventual septicemia y la enterocolitis necrozante. La leche materna también posee factores antiinflamatorios, que aunados a otros elementos contribuyen en el control de las infecciones gastrointestinales.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Pabst HF. Immunomodulation by breast-feeding. Pediatr Infect Dis J 1997; 16: 991.

2. Bernt KM, Walker WA. Human milk as a carrier of biochemical messages. Acta Pediatr Supl 1999; 430: 27-41.

3. Berseth CL, Lichtengerger LM, Morris FH. Comparison of the gastrointestinal growth promoting effects of rat colostrum and mature milk in newborn rats in vivo. Am J Clin Nutr 1983; 37: 52.

4. Berseth CL. Breastmilk enhanced intestinal and somatic growth in neonatal rats. Biol Neonate 1987; 51: 53-59.

5. Widdowson EM, Colomb VE, Artavanis CA. Changes in the organs of pigs in response to feeding for the first 24 h after birth. Biol Neonate 1976; 28: 272-281.

6. Glesson M, Crips AW, Clancy RL, Hensley AJD, Firman DW. Breast feeding conditions a differential developmental pattern of mucosal immunity. Clin Exp Immunol 1986; 66: 216-222.

7. Wold AE, Adlerberth I. Breast feeding and intestinal microflora of the infant-implications for protections against infectious diseases. Adv Exp Med Biol 2000; 478: 77-93.

8. Turesson I. Distribution of immunoglobulin-containing cells in human bone marrow and lymphoid tissues. Acta Med Scand 1976; 199: 293-304.

9. Pabst HF. Immunomodulation by breast-feeding. Pediatr Infect Dis J 1997; 16: 991-995.

10. Pierpaoli W, Kopp HG, Bianchi E. Interdependence of thymic and neuroendocrine functions in ontogeny. Clin Exp Immunol 1976; 24: 501-505.

11. Dickinson EC, Corga JC, Garret M, Tuncer R, Boyle P, Watkins SC, Alber SM, Parizhskaya M, Trucco M, Rowe MI, Ford HR. Immunoglobulin A supplementation abrogates bacterial translocation and preserves the architecture of the intestinal epithelium. Surgery 1998; 124: 284-290.

12. Garofalo RP, Goldman AS. Cytokines, chemokines, and colony-stimulating factors in human milk: the 1997 update. Biol Neonate 1978; 74: 134-142.

13. Editorial. Breastmilk endocrinology. J Trop Pediat 1996; 42: 2-4.

14. Kacsob B, Toth BE, Avery LM, Yamamuro Y, Grosvenor CE. Molecular heterogeneity of prolactin in lactating rats and their pups: biological and immunological activities in the pituitary gland, serum, and milk. Endocr Regul 1991; 25: 98-111.

15. Gala RR. Prolactin and growth hormone in the regulation of the immune system. Proc Soc Exp Biol Med 1991; 198: 513-517.

16. Wu G, Knabe DA, Flynn EN. Synthesis of citruline from glutamine in pig enterocytes. J Biochem 1994; 299: 115-121.

17. Wu G, Knabe DA. Free and protein-bound aminoacids in snow’s colostrum and milk. J Nutr 1994; 124: 415-424.

18. Grazioso CF, Buescher ES. Inhibition of neutrophil function by human milk. Cellular Immunology 1996; 168: 125-132.

19. Pruitt KM, Rahemtulla F, Mansson-Rahemutulla B. Innata humoral factors. In: Ogra Pl, Mesteky J, Lamm ME, Strober W, McGhee JR, editors. Handbook of mucosal immunology. 2nd edition. Academic Press, Inc; 53-70.

20. Ebrahim GJ. Breastmilk immunology. J Trop Pediatr 1995; 41: 2-4.

21. Draca S. Prolactin as an immunoreactive agent. Immunol and Cell Biol 1995; 73: 481-483.

22. Julius MH, Janunsz M, Lisowski J. A colostral protein that induces the growth and differentiation of resting B lymphocytes. J Immunol 1988; 140: 1366-1371.

23. Sembra RD, Juul SE. Erytropoietin in human milk: physiology and role in infant health. J Hum Lact 2002; 18: 252-261.