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Revista Médica Sinergia

2020, Número 08

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Revista Médica Sinergia 2020; 5 (08)


Síndrome de Lambert-Eaton paraneoplásico en carcinoma de células pequeñas de pulmón

González-Houdelath K, Varela MAC, Barrantes AGJ

Idioma: Español
Referencias bibliográficas: 24
Paginas: 1-9
Archivo PDF: 145.42 Kb.


RESUMEN

El síndrome miasténico de Lambert Eaton es una patología autoinmune paraneoplásica asociada mayormente a cáncer de pulmón, que se manifiesta con afectación de la unión neuromuscular y disfunciones autonómicas. Se presenta el caso de una paciente femenina de 58 años quien fue diagnosticada con cáncer de pulmón de células pequeñas y que posteriormente presentó la tríada clásica de síndrome miasténico de Lambert Eaton (debilidad proximal de miembros inferiores, disfunción autonómica e hiporreflexia). Se abordó mediante pruebas neurofisiológicas (electromiografía), confirmando su diagnóstico en asociación con el cuadro clínico. El caso presentado a continuación destaca la asociación de neoplasias pulmonares con el diagnóstico de síndrome miasténico de Lambert Eaton y la mejoría de los síntomas gracias al tratamiento sintomático y oncológico.


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