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Revista Médica Sinergia

2020, Number 08

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Revista Médica Sinergia 2020; 5 (08)

Paraneoplastic Lambert-Eaton syndrome in small cell carcinoma of the lung

González-Houdelath K, Varela MAC, Barrantes AGJ

Language: Spanish
References: 24
Page: 1-9
PDF size: 145.42 Kb.


ABSTRACT

Lambert Eaton myasthenic syndrome is a paraneoplastic autoimmune pathology mostly associated with lung cancer, which manifests itself with involvement of the neuromuscular junction and autonomic dysfunctions. We present the case of a 58-year-old female patient who was diagnosed with small cell lung cancer and who subsequently presented the classic Lambert Eaton myasthenic syndrome (proximal lower limb weakness, autonomic dysfunction, and hyporeflexia). It was approached through neurophysiological tests (electromyography), confirming its diagnosis in association with the clinical picture. The case presented below highlights the association of pulmonary neoplasms with the diagnosis of Lambert Eaton myasthenic syndrome and the improvement of symptoms thanks to symptomatic and oncological treatment.


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