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Revista Médica Sinergia

2020, Número 11

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Revista Médica Sinergia 2020; 5 (11)


Actualización en dermatitis atópica: líneas de tratamiento

López VS, Núñez PE, Chaverri PG

Idioma: Español
Referencias bibliográficas: 25
Paginas: 1-12
Archivo PDF: 256.68 Kb.


RESUMEN

La dermatitis atópica es la dermatosis inflamatoria más frecuente, con un pico de prevalencia en la niñez temprana y con mayor porcentaje de afectación en países industrializados. Entre las principales características de este trastorno crónico y/o recidivante se destacan, el prurito, la dermatitis eccematosa, el compromiso facial y de regiones extensoras en la niñez temprana, mientras que el eccema y liquenificación en pliegues es más usual en niños y adultos. En los últimos años ha habido un avance en el conocimiento de la patogenia, centrada en la vía Th2, pero con una participación significativa de la vía Th22 y de los ejes Th1 y Th17, de la disfunción de la barrera epidérmica, el prurito y la señalización JAK/STAT, este progreso ha condicionado innovaciones en los tratamientos tópicos y sistémicos.


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