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Federación Mexicana de Ginecología y Obstetricia, A.C.

2021, Number 06

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Ginecol Obstet Mex 2021; 89 (06)

Neuroglial tumors in pregnancy: a case report

Hernández-Lizarazo WA, Geney-Montes MC, Sacristán-Rodríguez PA, Garzón-Caicedo JF

Language: Spanish
References: 18
Page: 472-479
PDF size: 670.49 Kb.


ABSTRACT

Background: Neuroglial tumors comprise a heterogeneous group of neoplastic diseases, of which anaplastic astrocytoma accounts for 4% of all malignant tumors of central nervous system and 10% of all gliomas. Its annual incidence in the general population is 0.5 -0.7 per 100,000 inhabitants and is the ninth cause of cancer-related death in women of childbearing age. However, there are no epidemiological data during pregnancy and available treatments have been extrapolated from non-pregnant population and small series of cases in pregnant women.
Objective: To present a case report of a pregnant patient with a neuroglial tumor. Due to the infrequency of this pathology, its report and bibliographic review are interesting.
Clinical case: A 25-year-old patient, with gestation of 38 weeks and without medical records, debuted with a convulsive episode and a voluminous solid and cystic component lesion suggestive of an atypical primary cerebral process. Total gross resection was performed on day 10 of the puerperium with histopathological report consistent of grade III anaplastic astrocytoma.
Conclusion: High-grade gliomas during gestational period are rare and difficult to diagnose Histology of the lesion is the definitive diagnosis so the first-line treatment is neurosurgical resection of the entire tumor. A multidisciplinary team is required for its comprehensive management.


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