Gómez MJJ, Fosado RI

Language: Spanish
References: 5
Page: 51-55
PDF size: 62.80 Kb.

ABSTRACT

Introduction: Severe hepatic damage has been reported following isofluorane anaesthesia.
Objective: To evaluate the changes of hepatic tests after isofluorane anaesthesia in surgical patients.
Setting: Anesthesiology department of a tertiary care hospital, Monterrey, Mexico.
Design: Case series report.
Patients: Sixty patients were asigned to three groups: Control group, PD (n = 20) treated with peridural anestehesia; MN group (n= 20) received isofluorane anaesthesia during three hours or less; and MY group treated with isofluorane during a period major of three hours.
Measurements and main results: Aminotranferases (SGOT, SGPT), alkaline phosphatase and direct and indirect bilirrubine were measured at 0, three and 24 hours in all the patients. SGOT, SGPT, alkaline phophatase and direct and indirect bilirrubin remained unchanged in PD group. SGOT and SGPT had an important increase at three hours in MN and MY group (p ‹ 0.05) and no changes of the others parameter were observed.
Conclusion: Isofluorane anaesthesia produces alterations of liver function in surgical patients.

REFERENCES

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